Aortic valve calcification: association with bone mineral density and cardiovascular risk factors

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dc.authoridAkaycan, Jülide/0000-0002-9174-6777;
dc.authorwosidAkaycan, Jülide/ABI-2397-2020
dc.authorwosidyagmur, cengiz/HQZ-3472-2023
dc.authorwosidKutlusoy, Ergun/ABB-9017-2020
dc.authorwosidaksoy, yüksel/ABH-1304-2021
dc.contributor.authorAksoy, Y
dc.contributor.authorYagmur, C
dc.contributor.authorTekin, GO
dc.contributor.authorYagmur, J
dc.contributor.authorTopal, E
dc.contributor.authorKekilli, E
dc.contributor.authorTurhan, H
dc.date.accessioned2024-08-04T20:15:07Z
dc.date.available2024-08-04T20:15:07Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Cardiovascular risk factors are reported to increase the incidence of aortic valve calcification. Among older women, low bone mineral density appears to be associated with increased prevalence of aortic calcification. We aimed to assess and compare cardiovascular risk factors and bone mineral density of patients with and without aortic valve calcification. Materials: and methods Cardiovascular risk factors and bone mineral density measurements have been assessed in 49 patients with aortic valve calcification and in 65 patients without aortic valve calcification. All patients were subsequently referred to the nuclear medicine department to measure bone mineral density after echocardiographic evaluation. Results: No statistically significant differences were observed between the two groups with respect to sex, body mass index, history of coronary artery disease, diabetes mellitus, hypercholesterolemia, and smoking status. Although height and weight of the patients with aortic valve calcification were significantly lower than those of patients without aortic valve calcification, they were not independent risk factors. Age and hypertension were found to be independent positive risk factors for aortic valve calcification, whereas T score was found to be negatively associated with aortic valve calcification. Conclusion: We have shown that aortic valve calcification is positively associated with age and hypertension, whereas bone mineral density is negatively associated with aortic valve calcification. The mechanism underlying the association between decreased bone mineral density and aortic valve calcification remains to be clarified in further studies.en_US
dc.identifier.doi10.1097/00019501-200509000-00007
dc.identifier.endpage383en_US
dc.identifier.issn0954-6928
dc.identifier.issn1473-5830
dc.identifier.issue6en_US
dc.identifier.pmid16118543en_US
dc.identifier.scopus2-s2.0-28944433579en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage379en_US
dc.identifier.urihttps://doi.org/10.1097/00019501-200509000-00007
dc.identifier.urihttps://hdl.handle.net/11616/94184
dc.identifier.volume16en_US
dc.identifier.wosWOS:000232420300007en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofCoronary Artery Diseaseen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaortic valve calcificationen_US
dc.subjectosteoporosisen_US
dc.subjectcardiovascular risk factorsen_US
dc.subjectcalcificationen_US
dc.titleAortic valve calcification: association with bone mineral density and cardiovascular risk factorsen_US
dc.typeArticleen_US

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