Serum salusins levels are increased and correlated positively with cyst size in ovarian endometrioma

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dc.contributor.authorSahin, Levent
dc.contributor.authorBozkurt, Murat
dc.contributor.authorCelik, Onder
dc.contributor.authorCelik, Nilufer
dc.contributor.authorAydin, Suleyman
dc.contributor.authorGencdal, Servet
dc.date.accessioned2024-08-04T20:41:13Z
dc.date.available2024-08-04T20:41:13Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: The objective of this study is to evaluate plasma concentrations of salusin-alpha and salusin-beta levels in women with endometrioma and non-endometriotic benign ovarian cysts. Method: Endometrioma patients (n = 14), non-endometriotic ovarian cysts (n = 14), and age-matched normal healthy fertile subjects (n = 14) participated in this study. Plasma salusin-alpha and salusin-beta levels at the time of mid-luteal phase before and 3 months after L/S cystectomy were measured using ELISA and EIA tests, and their relation with demographic parameters was also assessed. Results: The mean salusin-alpha and salusin-beta levels were significantly higher in women with endometrioma before the removal of cyst compared with cases with non-endometriotic cyst and fertile cases. Surgical removal of the endometrioma decreased the mean salusin-alpha and salusin-beta levels to the level of those with non-endometriotic cyst before and after the cystectomy and fertile women, in both unilateral and bilateral endometrioma cases. Plasma salusin-beta concentrations were found to be positively correlated with age, size of cyst, bilaterality, and salusin-alpha levels. Salusin-beta values showed no correlations to BMI and size of the ovarian cysts. Conclusions: Plasma salusin-alpha and salusin-beta levels are increased in endometrioma patients and positively correlated with endometrioma size. Laparoscopic removal of the endometrioma by stripping technique decreases the salusin levels to a similar level of fertile women.en_US
dc.identifier.doi10.3109/09513590.2015.1029446
dc.identifier.endpage642en_US
dc.identifier.issn0951-3590
dc.identifier.issn1473-0766
dc.identifier.issue8en_US
dc.identifier.pmid26008602en_US
dc.identifier.scopus2-s2.0-84942771179en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage639en_US
dc.identifier.urihttps://doi.org/10.3109/09513590.2015.1029446
dc.identifier.urihttps://hdl.handle.net/11616/96994
dc.identifier.volume31en_US
dc.identifier.wosWOS:000369941900014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofGynecological Endocrinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAngiogenesisen_US
dc.subjectendometriosisen_US
dc.subjectinfertilityen_US
dc.subjectovaryen_US
dc.subjectsalusinsen_US
dc.titleSerum salusins levels are increased and correlated positively with cyst size in ovarian endometriomaen_US
dc.typeArticleen_US

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