Evaluation of the effects of platelet-rich fibrin, concentrated growth factors, and autologous fibrin glue application on wound healing following gingivectomy and gingivoplasty operations: a randomized controlled clinical trial

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dc.authoridBozkurt, Esra/0000-0002-6131-9061
dc.authorwosidBozkurt, Esra/ISU-4354-2023
dc.contributor.authorBozkurt, Esra
dc.contributor.authorUslu, Mustafa Ozay
dc.date.accessioned2024-08-04T20:51:46Z
dc.date.available2024-08-04T20:51:46Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to evaluate the effect of platelet-rich fibrin (PRF), concentrated growth factors (CGF), and autologous fibrin glue (AFG) application on early wound healing after gingivectomy and gingivoplasty operations. Method and materials: In this split-mouth study, gingivectomy and gingivoplasty surgery were performed on 19 patients. The postoperative PRF, CGF, and AFG applied areas were compared with the control regions. On days 0, 7, 14, and 28, the surgical area was stained with a plaque-disclosing agent and evaluated in the Image) program. Wound healing was evaluated with H2O2 test, visual analog scale for pain, and Landry, Turnbull, and Howley (LTH) wound healing index on days 7, 14, and 28. The patients were asked to evaluate their esthetic perceptions on a visual analog scale. Results: The amount of staining at days 7 and 14 was found to be significantly higher in the control group than in the test groups, but there was no difference between the test groups. LTH index values of the control group at days 7, 14, and 28 were found to be significantly lower than the test groups. There was no significant difference between the groups in the epithelialization assessment performed with the H2O2 test. It was observed that the use of platelet concentrate at day 7 reduced postoperative early pain. Patients were highly satisfied with postoperative esthetics. Conclusion: After gingivectomy and gingivoplasty operations, PRF, CGF, and AFG application were found to have positive effects on wound healing. However, PRF, CGF, and AFG applications were not superior to each other in terms of secondary wound healing.en_US
dc.identifier.doi10.3290/j.qi.b2449819
dc.identifier.endpage341en_US
dc.identifier.issn0033-6572
dc.identifier.issn1936-7163
dc.identifier.issue4en_US
dc.identifier.pmid34927405en_US
dc.identifier.scopus2-s2.0-85126389557en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage328en_US
dc.identifier.urihttps://doi.org/10.3290/j.qi.b2449819
dc.identifier.urihttps://hdl.handle.net/11616/100536
dc.identifier.volume53en_US
dc.identifier.wosWOS:000800290300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherQuintessence Publishing Co Incen_US
dc.relation.ispartofQuintessence Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectautologous fibrin glueen_US
dc.subjectconcentrated growth factoren_US
dc.subjectgingivectomyen_US
dc.subjectgingivoplastyen_US
dc.subjectplatelet-rich fibrinen_US
dc.titleEvaluation of the effects of platelet-rich fibrin, concentrated growth factors, and autologous fibrin glue application on wound healing following gingivectomy and gingivoplasty operations: a randomized controlled clinical trialen_US
dc.typeArticleen_US

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