Toxic effects of deltamethrin and ?-cyhalothrin on Xenopus laevis tadpoles

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dc.authoridGüngördü, Abbas/0000-0001-7770-0660
dc.authoridOzmen, Murat/0000-0003-4378-0839
dc.authorwosidGüngördü, Abbas/A-3009-2015
dc.authorwosidOZMEN, MURAT/A-4874-2009
dc.contributor.authorAydin-Sinan, Handan
dc.contributor.authorGungordu, Abbas
dc.contributor.authorOzmen, Murat
dc.date.accessioned2024-08-04T20:35:50Z
dc.date.available2024-08-04T20:35:50Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study evaluates the toxic effects of deltamethrin and lambda-cyhalothrin on Xenopus laevis tadpoles after 168 h of exposure. The LC50 of deltamethrin and lambda-cyhalothrin at 168 h was calculated as the mu g of active ingredient per liter (mu g AI/L). According to these values, the LC50 was 6.26 and 3.94 mu g AI/L for deltamethrin and lambda-cyhalothrin, respectively. Several enzymes were studied for early signs of intoxication following exposure to the pesticides for 24 h. Glutathione-S-transferase, carboxylesterase, and lactate dehydrogenase were inhibited by lambda-cyhalothrin, and both pesticides inhibited acid phosphatase and aspartate aminotransferase. In contrast, acetylcholinesterase was activated by deltamethrin. The results suggest that X. laevis is sensitive to the pyrethroids that were tested, and the enzyme responses suggest that they are potential biomarkers for evaluating the toxic effect of pyrethroids on amphibians in environmental conditions.en_US
dc.identifier.doi10.1080/03601234.2012.648545
dc.identifier.endpage402en_US
dc.identifier.issn0360-1234
dc.identifier.issn1532-4109
dc.identifier.issue5en_US
dc.identifier.pmid22424064en_US
dc.identifier.scopus2-s2.0-84859354710en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage397en_US
dc.identifier.urihttps://doi.org/10.1080/03601234.2012.648545
dc.identifier.urihttps://hdl.handle.net/11616/95607
dc.identifier.volume47en_US
dc.identifier.wosWOS:000303579200005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofJournal of Environmental Science and Health Part B-Pesticides Food Contaminants and Agricultural Wastesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectXenopus laevisen_US
dc.subjectdeltamethrinen_US
dc.subjectlambda-cyhalothrinen_US
dc.subjectbiomarkersen_US
dc.titleToxic effects of deltamethrin and ?-cyhalothrin on Xenopus laevis tadpolesen_US
dc.typeArticleen_US

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