Pituitary volume in patients with panic disorder

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dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authoridkartalcı, şükrü/0000-0003-2560-0355
dc.authoridUnal, Suheyla/0000-0003-3266-6256
dc.authoridUnal, Suheyla/0000-0003-3266-6256;
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.authorwosidkartalcı, şükrü/ABI-1106-2020
dc.authorwosidUnal, Suheyla/JVO-8367-2024
dc.authorwosidUnal, Suheyla/HJH-7559-2023
dc.authorwosidUnal, Suheyla/AAS-2388-2020
dc.authorwosidAtmaca, Murad/V-9377-2018
dc.contributor.authorKartalci, Sukru
dc.contributor.authorDogan, Metin
dc.contributor.authorUnal, Suheyla
dc.contributor.authorOzcan, A. Cemal
dc.contributor.authorOzdemir, Serdal
dc.contributor.authorAtmaca, Murad
dc.date.accessioned2024-08-04T20:32:41Z
dc.date.available2024-08-04T20:32:41Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPanic patients have many functional deficiencies in the hypothalamic-pituitary-adrenal (HPA) axis. Previous studies have shown changed pituitary gland volume in some psychiatric disorders that have functional deficiencies in the HPA axis: However, to date no study has evaluated the pituitary gland volume in patients with panic disorder (PD). We investigated the pituitary gland volume in patients with PD (n = 27) and age- and sex-matched healthy controls (n = 27), using 1.5-T magnetic resonance imaging in this study. Analysis showed that patients with PD had significantly smaller pituitary volume compared to healthy subjects. Patients with agoraphobia especially had a significantly smaller pituitary volume than patients without agoraphobia. There was a significant relationship between the pituitary volume and both the severity of symptoms and the illness duration in the patient group. The results show that patients with PD have reduced pituitary volume, which may reflect the functional abnormalities seen in this disorder. These findings may help us better understand the pathology of PD. (C) 2010 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.pnpbp.2010.11.005
dc.identifier.endpage207en_US
dc.identifier.issn0278-5846
dc.identifier.issn1878-4216
dc.identifier.issue1en_US
dc.identifier.pmid21075158en_US
dc.identifier.scopus2-s2.0-78650943534en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage203en_US
dc.identifier.urihttps://doi.org/10.1016/j.pnpbp.2010.11.005
dc.identifier.urihttps://hdl.handle.net/11616/95230
dc.identifier.volume35en_US
dc.identifier.wosWOS:000287271400029en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofProgress in Neuro-Psychopharmacology & Biological Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAgoraphobiaen_US
dc.subjectHPA axisen_US
dc.subjectMagnetic resonance imagingen_US
dc.subjectPanic disorderen_US
dc.subjectPituitary gland volumeen_US
dc.titlePituitary volume in patients with panic disorderen_US
dc.typeReview Articleen_US

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