A Chryseobacterium meningosepticum outbreak in a neonatal ward

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dc.authoridOzen, Metehan/0000-0003-4088-3103
dc.authoridDURMAZ, RIZA/0000-0001-6561-778X
dc.authorwosidOzen, Metehan/X-2705-2018
dc.authorwosidDURMAZ, Rıza/HJH-4918-2023
dc.authorwosidOzen, Metehan/E-2610-2016
dc.contributor.authorGüngör, S
dc.contributor.authorÖzen, M
dc.contributor.authorAkinci, A
dc.contributor.authorDurmaz, R
dc.date.accessioned2024-08-04T20:13:26Z
dc.date.available2024-08-04T20:13:26Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: To report epidemiologic, bacteriologic, and clinical features of a Chryseobacterium meningosepticum outbreak. DESIGN: Outbreak investigation. SETTING: A neonatal intensive care unit (NICU) of a referral teaching hospital. METHODS: During 2 weeks in September 2001, four neonates in the NICU developed sepsis and underwent laboratory investigation. Multiple samples were obtained for cultures from endotracheal tubes, mechanical ventilators and humidifier boxes, infant incubators, parenteral and antiseptic solutions, feeding bottles, sinks, faucets, doors, and healthcare workers. RESULTS: C. meningosepticum was isolated from the blood cultures of four patients. The first isolate was identified 5 days after the death of the index case. Although all isolates were ciprofloxacin susceptible in vitro, the remaining three patients did not respond to ciprofloxacin therapy given for 6 or 7 days. Therapy was switched to vancomycin and rifampin and all three patients survived, with one having a complication (hydrocephalus). Environmental surveillance revealed C. meningosepticum in the stock lipid solution as the source of the epidemic. The outbreak was controlled after discontinuation of intravenous lipid solution, restriction of further neonatal admissions, and thorough disinfection of the unit and its equipment. CONCLUSION: Early identification of an epidemic and its source is important in avoiding morbidity and mortality. A contaminated lipid stock bottle was the source of this outbreak associated with multiple cases and one death.en_US
dc.identifier.doi10.1086/502261
dc.identifier.endpage617en_US
dc.identifier.issn0899-823X
dc.identifier.issn1559-6834
dc.identifier.issue8en_US
dc.identifier.pmid12940584en_US
dc.identifier.scopus2-s2.0-0042431623en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage613en_US
dc.identifier.urihttps://doi.org/10.1086/502261
dc.identifier.urihttps://hdl.handle.net/11616/93596
dc.identifier.volume24en_US
dc.identifier.wosWOS:000184767800017en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofInfection Control and Hospital Epidemiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFlavobacterium-Meningosepticumen_US
dc.subjectNewbornen_US
dc.subjectTherapyen_US
dc.titleA Chryseobacterium meningosepticum outbreak in a neonatal warden_US
dc.typeArticleen_US

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