Living Donor Liver Transplantation for Acute Liver Failure in Pediatric Patients Caused by the Ingestion of Fireworks Containing Yellow Phosphorus

dc.authoridYILMAZ, Mehmet/0000-0002-5710-5263
dc.authoridAtes, Mustafa/0000-0003-2821-453X
dc.authoridÖzgör, Dinçer/0000-0001-8519-8869
dc.authoridIsik, Burak/0000-0002-2395-3985
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidYILMAZ, Mehmet/HKM-4739-2023
dc.authorwosidAtes, Mustafa/ABI-5100-2020
dc.authorwosidÖzgör, Dinçer/AAB-3523-2021
dc.authorwosidYilmaz, Mehmet/AAF-6095-2021
dc.authorwosidIsik, Burak/A-6657-2018
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.contributor.authorAtes, Mustafa
dc.contributor.authorDirican, Abuzer
dc.contributor.authorOzgor, Dincer
dc.contributor.authorAydin, Cemalettin
dc.contributor.authorIsik, Burak
dc.contributor.authorAra, Cengiz
dc.contributor.authorYilmaz, Mehmet
dc.date.accessioned2024-08-04T20:35:41Z
dc.date.available2024-08-04T20:35:41Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractYellow phosphorus is a protoplasmic toxicant that targets the liver. The ingestion of fireworks containing yellow phosphorus, either by children who accidentally consume them or by adults who are attempting suicide, often results in death due to acute liver failure (ALF). We present the outcomes of 10 children who ingested fireworks containing yellow phosphorus. There were 6 boys and 4 girls, and their ages ranged from 21 to 60 months. One patient remained stable without liver complications and was discharged. Three patients died of hepatorenal failure and cardiovascular collapse, and living donor liver transplantation (LDLT) was performed for 6 patients. The patients had grade II or III encephalopathy, a mean alanine aminotransferase level of 1148.2 IU/L, a mean aspartate aminotransferase level of 1437.5 IU/L, a mean total bilirubin level of 6.9 mg/dL, a mean international normalized ratio of 6.6, a mean Pediatric End-Stage Liver Disease score of 33.7, and a mean Child-Pugh score of 11.3. Postoperatively, 2 patients had persistent encephalopathy and died on the second or third postoperative day, and 1 patient died of cardiac arrest on the first postoperative day despite a well-functioning graft. The other 3 patients were still alive at a mean of 204 days. In conclusion, the ingestion of fireworks containing yellow phosphorus causes ALF with a high mortality rate. When signs of irreversible ALF are detected, emergency LDLT should be considered as a lifesaving procedure; however, if yellow phosphorus toxicity affects both the brain and the heart in addition to the liver, the mortality rate remains very high despite liver transplantation. Liver Transpl 17:1286-1291, 2011. (C) 2011 AASLD.en_US
dc.identifier.doi10.1002/lt.22384
dc.identifier.endpage1291en_US
dc.identifier.issn1527-6465
dc.identifier.issue11en_US
dc.identifier.pmid21761550en_US
dc.identifier.scopus2-s2.0-82955161538en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1286en_US
dc.identifier.urihttps://doi.org/10.1002/lt.22384
dc.identifier.urihttps://hdl.handle.net/11616/95501
dc.identifier.volume17en_US
dc.identifier.wosWOS:000296701600005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofLiver Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectWhite Phosphorusen_US
dc.subjectBurnen_US
dc.titleLiving Donor Liver Transplantation for Acute Liver Failure in Pediatric Patients Caused by the Ingestion of Fireworks Containing Yellow Phosphorusen_US
dc.typeArticleen_US

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