Evaluation of emm gene types toxin gene profiles and clonal relatedness of group A streptococci

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dc.authorid101949en_US
dc.contributor.authorMengeloğlu, Fırat Zafer
dc.contributor.authorAktaş, Elif
dc.contributor.authorOtlu, Barış
dc.contributor.authorCömert, Füsun
dc.contributor.authorKülah, Canan
dc.contributor.authorTaş, Ebru
dc.contributor.authorSümbüloğlu, Vildan
dc.date.accessioned2017-07-14T07:07:50Z
dc.date.available2017-07-14T07:07:50Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractTh e aim of this study is to evaluate antibiotic susceptibilities, emm gene types, toxin gene profi les and clonal relatedness of group A streptococci (GAS) isolates obtained from patients and carriers. A total of  clinical isolates from patients and  isolates from carriers were included in the study. Emm typing, toxin gene detection for speA, speB, speC, speG and smeZ genes and pulsed-fi eld gel electrophoresis (PFGE) was performed. Twenty-one distinct emm types were detected; the most common types were emm, emm, emm, emm, emm and emm. Th e detection rates of both emm types and the toxin genes didn’t diff er signifi cantly between patients and carriers. Th e presence of speA and smeZ was signifi cantly higher in emm and speG was signifi cantly lower in emm when compared to the other emm types. Th e rate of clustering obtained with PFGE wasn’t signifi cantly diff erent in patients and carriers. As a result, twelve of the  emm types detected in this study were covered by the -valent vaccine, constituting . of the emm typeable isolates; however the emm type which is one of the most common types in the present study is not among this coverage.en_US
dc.identifier.citationMengeloğlu, F. Z. Aktaş, E. Otlu, B. Cömert, F. Külah, C. Taş, E. Sümbüloğlu, V. (2013). Evaluation of emm gene types toxin gene profiles and clonal relatedness of group A streptococci. Bosnian Journal of Basic Medical Sciences. 13 (3); 163-169.en_US
dc.identifier.endpage169en_US
dc.identifier.issue3en_US
dc.identifier.startpage163en_US
dc.identifier.urihttps://hdl.handle.net/11616/7370
dc.identifier.volume13en_US
dc.language.isoenen_US
dc.publisherBosnian Journal of Basic Medical Sciencesen_US
dc.relation.ispartofBosnian Journal of Basic Medical Sciencesen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGroup A streptococcien_US
dc.subjectEmm typingen_US
dc.subjectToxin genesen_US
dc.subjectSpeAen_US
dc.subjectSpeBen_US
dc.subjectSpeCen_US
dc.subjectClonal relationen_US
dc.subjectPFGEen_US
dc.titleEvaluation of emm gene types toxin gene profiles and clonal relatedness of group A streptococcien_US
dc.typeArticleen_US

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