Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study
| dc.contributor.author | Akcan, Alper Celal | |
| dc.contributor.author | Patmano, Mehmet | |
| dc.contributor.author | Oz, Abdullah Bahadir | |
| dc.contributor.author | Arikan, Turkmen Bahadir | |
| dc.contributor.author | Gun, Iskender | |
| dc.contributor.author | Dogan, Serap | |
| dc.contributor.author | Sozuer, Erdogan | |
| dc.date.accessioned | 2022-03-08T09:32:46Z | |
| dc.date.available | 2022-03-08T09:32:46Z | |
| dc.date.issued | 2019 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: To compare therapeutic effectiveness of surgery alone with surgery plus corticosteroid in patients with granulomatous mastitis.Material and Methods: The study included 30 patients aged 23-60 years. The patients were randomly assigned into two groups by lot. In-group 1, the patients received 375 mg ampicillin-sulbactam (twice daily, p.o.) for a week; than 32 mg prednisolone was started which was gradually tapered (biweekly by 8 mg) over 8 weeks. Surgery was performed 2 weeks after tapering. In-group 2, the patients received 375 mg ampicillin-sulbactam (twice daily, p.o.) for a week and underwent surgery. During 2-years follow-up, all patients were assessed for etiological factors and recurrence.Results: No significant differences was found in demographic characteristics, smoking habits, oral contraceptive use, presenting complaints, physical examination findings, localization and diagnostic tools used between groups. During follow-up, recurrence was seen in one patient (6.7%) in surgery group and in 3 patients (20%) in steroid group but no significant difference was detected between groups (p>0.05). Conclusion: In patients with granulomatous mastitis, systemic steroid therapy is an effective modality in patients unresponsive to antibiotic therapy after ruling out tuberculosis. | en_US |
| dc.identifier.citation | Patmano, M., Akcan, A., Bahadir Oz, A., Bahadir Arikan, T., Dogan, S., Gun, I., & Sozuer, E. (2021). Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study . Annals of Medical Research | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/54728 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Comparison of surgery and surgery plus corticosteroid therapy in idiopathic granulomatous mastitis, prospective randomized study | en_US |
| dc.type | Article | en_US |
