Chronic low-frequency electromagnetic field exposure before and after neonatal life induces changes on blood oxidative parameters of rat offspring
| dc.contributor.author | Guleken, Zozan | |
| dc.date.accessioned | 2022-03-15T11:24:23Z | |
| dc.date.available | 2022-03-15T11:24:23Z | |
| dc.date.issued | 2021 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: It is aimed to investigate the chronic effects of extremely low-frequency magnetic fields (ELF-MF) exposure on blood oxidative and anti-oxidative levels. Rat offsprings during intrauterine (IU) and extrauterine (EU) period exposure to chronic 50 Hz electromagnetic fields included to the study to see the ELF-MF induced changes in blood biochemical levels. To evaluate the cell’s physiological response, the levels of glutathione (GSH) and malondialdehyde (MDA) were measured as a label. Recently, the use of electromagnetic (EM) energy has increased in worldwide. Numerous reports indicate that prenatal and postnatal period repetitive ELF-MF leads to health-related issues on physiological responses and affect the activity of the enzymes.Materials and Methods: Pregnant female Wistar Albino rats (n = 21), weighing 250 – 300 g were randomly divided into MF exposed group (Group I) and sham group (Group II). Eleven pregnant females were exposed to MF for 24 hours a day for IU exposure and exposed to 50 Hz 500μT ELF-MF radiating magnetic field cages for 24 hours for the duration of pregnancy for 21 days. Following the birth, first generation newborn rats (n=11) were continued to expose 50 Hz 500μT ELF-MF, 24 hours, for additional 50 days in EU period. Sham group (n=10) without any radiation. Groups’ blood samples were collected and analyzed. The levels of an oxidative stress marker MDA and antioxidant scavenger GSH activities were investigated. Results: Long-term exposure to ELF-MF increased MDA concentration in blood plasma of rat offspring and decreased GSH levels significantly. No correlation was shown between MDA and GSH levels. Conclusion: Long-term ELF-MF exposure causes oxidative stress that results an increase on lipid peroxidation and a reduction on antioxidative parameters of blood tissue. | en_US |
| dc.identifier.citation | Guleken, Z. (2021). Chronic low-frequency electromagnetic field exposure before and after neonatal life induces changes on blood oxidative parameters of rat offspring . Annals of Medical Research | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/55671 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Chronic low-frequency electromagnetic field exposure before and after neonatal life induces changes on blood oxidative parameters of rat offspring | en_US |
| dc.type | Article | en_US |
