Autoimmune polyglandular syndrome type III which accompanies to multiple sclerosis: A case report

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Küçük Resim

Tarih

2019

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Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Abstract: Autoimmune polyglandular syndrome type III (APS III) is characterised by autoimmune destruction of various endocrine and nonendocrine tissues. It differs from APS I and APS II in terms of without adrenal involvement. Although APS III includes a series ofautoimmune disorders, it is rarely associated with multiple sclerosis (MS). A 41-year-old female patient had diplopia, visual blurring,dizziness, and giddiness for 2 weeks. In her medical history, she had a diagnosis of MS and using Teriflunomide. It was detectedpositivity of antinuclear antibody (ANA), anti-thyroid peroxidase (Anti-TPO) and anti-thyroglobulin (Anti-TG) antibodies. Based onthese results, the patient with MS who has chronic autoimmune thyroiditis and primary ovarian failure was diagnosed with APSIII. The coexistence of APS-III and MS is a rare clinical entity. Moreover, hypothyroidism has been detected during teriflunomidetherapy in the patient. Hypothyroidism was most likely a component of APS-III in our case, but it may also have been triggered byteriflunomide.

Açıklama

Anahtar Kelimeler

Kaynak

Annals of Medical Research

WoS Q Değeri

Scopus Q Değeri

Cilt

26

Sayı

12

Künye

GÖRGEL A,TECELLİOĞLU M,ÇANKAYA C (2019). Autoimmune polyglandular syndrome type III which accompanies to multiple sclerosis: A case report. Annals of Medical Research, 26(12), 3053 - 3057. Doi: 10.5455/annalsmedres.2019.07.420