Nebivolol in preventing atrial fibrillation following coronary surgery in patients over 60 years of age

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dc.authoriddisli, olcay murat/0000-0002-9699-4817
dc.authoridErdil, Nevzat/0000-0002-8275-840X
dc.authoridDönmez, Köksal/0000-0003-1554-0141;
dc.authorwosiddisli, olcay murat/ABI-3289-2020
dc.authorwosidErdil, Nevzat/K-8079-2019
dc.authorwosidDönmez, Köksal/U-8573-2019
dc.authorwosidBattaloglu, Bektas/ABI-6211-2020
dc.contributor.authorErdil, Nevzat
dc.contributor.authorKaynak, Murat
dc.contributor.authorDonmez, Koksal
dc.contributor.authorDisli, Olcay Murat
dc.contributor.authorBattaloglu, Bektas
dc.date.accessioned2024-08-04T20:40:07Z
dc.date.available2024-08-04T20:40:07Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Postoperative atrial fibrillation is a common complication after cardiac surgery, with an incidence as high as 20-50%. Increased age is associated with a significant increase in postoperative atrial fibrillation risk. This common complication is associated with higher morbidity and mortality rates. The aim of this study was to assess the efficacy of nebivolol in preventing atrial fibrillation following coronary artery bypass surgery in patients over 60 years of age. Methods: In this prospective randomized study, 200 patients who were candidates for elective coronary artery bypass surgery were divided into two groups. The first group was administered with nebivolol and the second group was administered with metoprolol. Treatment was initiated four days prior to surgery, and patients were monitored for atrial fibrillation until discharge. Forty-one patients recieved 50 mg metoprolol succinate daily, which was initiated minimum 4 days before surgery. Results: Demographic data were similar in both groups. The incidence of postoperative atrial fibrillation in both groups was similar, with no significant difference being identified [n=20 (20%); n=18 (18%), P=0.718; respectively]. There were not any mortality at both groups during study. Inotropic agent requirement at ICU was similar for both groups [n=12 (12%), n=18 (18%), P=0.32]. Conclusion: We compared the effectiveness of nebivolol and metoprolol in decreasing the incidence of postoperative atrial fibrillation, and determined that nebivolol was as effective as metoprolol in preventing postoperative atrial fibrillation at patients. Nebivolol may be the drug of choice due to its effects, especially after elective coronary artery bypass surgery.en_US
dc.identifier.doi10.5935/1678-9741.20140078
dc.identifier.endpage587en_US
dc.identifier.issn0102-7638
dc.identifier.issn1678-9741
dc.identifier.issue4en_US
dc.identifier.pmid25714213en_US
dc.identifier.scopus2-s2.0-84923642374en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage581en_US
dc.identifier.urihttps://doi.org/10.5935/1678-9741.20140078
dc.identifier.urihttps://hdl.handle.net/11616/96697
dc.identifier.volume29en_US
dc.identifier.wosWOS:000350904300017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSoc Brasil Cirurgia Cardiovascen_US
dc.relation.ispartofRevista Brasileira De Cirurgia Cardiovascularen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCoronary Artery Bypassen_US
dc.subjectAtrial Fibrillationen_US
dc.subjectAnti-Arrhythmia Agentsen_US
dc.subjectDrug Therapyen_US
dc.titleNebivolol in preventing atrial fibrillation following coronary surgery in patients over 60 years of ageen_US
dc.typeArticleen_US

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