Serum asymmetric-dimethylarginine, apelin and NT-pro BNP levels in dialysis patients

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dc.authoridDogan, Abdulahad/0000-0002-5438-8560
dc.authorwosidDogan, Abdulahad/ACO-8746-2022
dc.contributor.authorBentli, R.
dc.contributor.authorTaskapan, H.
dc.contributor.authorTaskapan, M. C.
dc.contributor.authorDogan, A.
dc.date.accessioned2024-08-04T20:49:05Z
dc.date.available2024-08-04T20:49:05Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: The relationships among serum Apelin, Asymmetric- dimethylarginine (ADMA), N-terminal probrain natriureticpeptide (NT-proBNP) levels, and blood pressures in dialysis patients are not well known. Materials and Methods: Age and sex matched 30 hemodialysis (HD), 30 peritoneal dialysis (PD) patients, and 20 healthy controls were recruited. Serum apelin-36, ADMA, NT-proBNP levels, and blood pressures of both patients and healthy controls were measured and compared. Results: Serum ADMA and Apelin levels in HD patients were significantly higher than in PD patients. In multiple regression analyses the predictors of higher serum apelin levels were higher BMI, higher ADMA and lower systolic blood pressure. The predictors of serum ADMA levels were being on HD. The predictors of serum NT-proBNP levels were lower serum albumin and higher systolic blood pressure. Conclusion: Being on HD is a predictor of high ADMA levels. HD might be less effective on ADMA removal than PD. It seems that higher serum apelin levels related with lower sytolic blood pressure levels, whereas higher NT-proBNP levels related with higher sytolic blood pressure levels indicating potential roles as independent prognostic factors for systolic hypertension in dialysis patients.en_US
dc.description.sponsorshipInonu University Medical Research Centeren_US
dc.description.sponsorshipThis study was supported by Inonu University Medical Research Center.en_US
dc.identifier.doi10.4103/njcp.njcp_171_19
dc.identifier.endpage1547en_US
dc.identifier.issn1119-3077
dc.identifier.issue11en_US
dc.identifier.pmid33221779en_US
dc.identifier.scopus2-s2.0-85096629042en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1542en_US
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_171_19
dc.identifier.urihttps://hdl.handle.net/11616/99645
dc.identifier.volume23en_US
dc.identifier.wosWOS:000617096500010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofNigerian Journal of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectApelinen_US
dc.subjectasymmetric dimethylarginineen_US
dc.subjectblood pressureen_US
dc.subjectdialysisen_US
dc.subjectNT-proBNPen_US
dc.titleSerum asymmetric-dimethylarginine, apelin and NT-pro BNP levels in dialysis patientsen_US
dc.typeArticleen_US

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