Local Asymptotic Stability and Sensitivity Analysis of a New Mathematical Epidemic Model Without Immunity

dc.contributor.authorÇakan, Sümeyye
dc.date.accessioned2024-08-04T19:53:15Z
dc.date.available2024-08-04T19:53:15Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWith this study it is aimed to introduce and analyze a new SIS epidemic model including vaccination effect. Vaccination considered in the model provides a temporary protection effect and is administered to both susceptible and new members of the population. The study provides a different aspect to the SIS models used to express, mathematically, some infectious diseases which are not eradicated by the immune system. The model given this study is designed by considering varying processes from person to person in the disease transmission, the recovery from disease (recovery without immunity) and in the loss of protective effect provided by the vaccine. The processes that change according to individuals are explained by distributed delays used in the relevant differential equations that provide the transition between compartments. The differences in the model are especially evident in these parts. In analyzing the model, firstly, the disease-free and endemic equilibrium points related to the model are determined. Then, the basic reproduction number R? is calculated with the next generation matrix method. Next, the dynamics about locally asymptotically stable of the model at the disease-free and endemic equilibriums are examined according to the basic reproduction number R?. Attempts intended to reduce the spread of the disease are, of course, in the direction supporting the lowering the value R0. In this context, the reducing and enhancing effects of the parameters used in the model on the value R? have been interpreted mathematically and suggestions were made to implement control measures in this direction. Also, in order to evaluate the support provided by the vaccine during the spread of the disease, the model has been examined as vaccinated and unvaccinated, and by some mathematical process, it has been seen that the vaccination has a crucial effect on disease control by decreasing the basic reproduction number. In other respects, by explored that the effect of parameters related to vaccination on the change of R?, a result about the minimum vaccination ratio of new members required for the elimination of the disease in the population within the scope of the target of R?<1 has been obtained.en_US
dc.identifier.doi10.36753/mathenot.935016
dc.identifier.endpage62en_US
dc.identifier.issn2147-6268
dc.identifier.issue1en_US
dc.identifier.startpage50en_US
dc.identifier.trdizinid1186893en_US
dc.identifier.urihttps://doi.org/10.36753/mathenot.935016
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1186893
dc.identifier.urihttps://hdl.handle.net/11616/89591
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMathematical Sciences and Applications E-Notesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleLocal Asymptotic Stability and Sensitivity Analysis of a New Mathematical Epidemic Model Without Immunityen_US
dc.typeArticleen_US

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