Adhesion formation after microlaparoscopic and laparoscopic ovarian coagulation for polycystic ovary disease

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dc.authorwosidtaskin, omur/C-6864-2016
dc.contributor.authorTaskin, O
dc.contributor.authorSadik, S
dc.contributor.authorOnoglu, A
dc.contributor.authorGokdeniz, R
dc.contributor.authorYilmaz, I
dc.contributor.authorBurak, F
dc.contributor.authorWheeler, JM
dc.date.accessioned2024-08-04T20:12:02Z
dc.date.available2024-08-04T20:12:02Z
dc.date.issued1999
dc.departmentİnönü Üniversitesien_US
dc.description.abstractStudy Objective. To compare the effects of microlaparoscopy and decreased CO2 exposure on peritoneal microcirculation and potential adhesion formation after ovarian surgery with those of conventional operative laparoscopy. Design. Prospective, randomized study (Canadian Task Force classification I). Setting. Teaching hospital. Patients. Eighteen women with polycystic ovary disease. Interventions. Microlaparoscopic or laparoscopic ovarian coagulation of the ovaries. Measurements and Main Results. Approximately 10 to 12 coagulation points were applied to each ovary. Two to 3 weeks after the initial surgery second-look microlaparoscopy was performed to determine the extent of adhesions in both groups. The frequency of adhesion formation and changes in glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) levels were studied in homogenized peritoneal tissues obtained during surgery in each group. Results. Clinical profiles were similar between groups. Mean exposure, amount, and pressure of CO2 were significantly less in the microlaparoscopy group (p <0.05). The laparoscopy group had significantly more adhesions than the microlaproscopy group (24% vs 48%, p <0.05). The GSH-Px, SOD, CAT, and GSH levels were significantly lower in the laparoscopy group (0.425 mu mol, 1.2 ng, 37.55 mu mol, and 0.9 nmol vs 0.755 mu mol, 2.1 ng, 625 mu mol, and 2.6 nmol, respectively). Conclusion. Reduced exposure to and amount of CO2 during microlaparoscopy may result in decreased adhesion formation compared with conventional laparoscopy. This effect may possibly be due to lack of or minimal adverse effects on peritoneal microcirculation and cell-protective systems, which are proposed mechanisms for adhesion formation and closely related to peritoneal injury. In addition, microlaparoscopy may be a cost-effective alternative to conventional laparoscopy.en_US
dc.identifier.doi10.1016/S1074-3804(99)80095-4
dc.identifier.endpage163en_US
dc.identifier.issn1074-3804
dc.identifier.issue2en_US
dc.identifier.pmid10226125en_US
dc.identifier.scopus2-s2.0-0033059995en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage159en_US
dc.identifier.urihttps://doi.org/10.1016/S1074-3804(99)80095-4
dc.identifier.urihttps://hdl.handle.net/11616/93179
dc.identifier.volume6en_US
dc.identifier.wosWOS:000080684700006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJournal Amer Assoc Gynecologic Laparoscopistsen_US
dc.relation.ispartofJournal of The American Association of Gynecologic Laparoscopistsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFree-Radicalsen_US
dc.subjectWedge Resectionen_US
dc.subjectElectrocoagulationen_US
dc.subjectReperfusionen_US
dc.subjectSurfaceen_US
dc.subjectWomenen_US
dc.titleAdhesion formation after microlaparoscopic and laparoscopic ovarian coagulation for polycystic ovary diseaseen_US
dc.typeArticleen_US

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