The comparison of topical ibopamine 2% with tonography to identify the outflow resistance in eyes with ocular hypertension

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dc.contributor.authorHepsen, IF
dc.contributor.authorYilmaz, H
dc.contributor.authorKeskin, UC
dc.date.accessioned2024-08-04T20:14:44Z
dc.date.available2024-08-04T20:14:44Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: To evaluate the ability of topical ibopamine 2% to detect outflow resistance by comparing it with the tonography test in eyes with ocular hypertension (OHT). Methods: 62 eyes with OHT and 33 control eyes were included in this prospective study. Tonography was done manually as a standard outflow facility measurement. We used a C value of 0.18 mu l/min/ mm Hg or less and a P-o/C value of 100 and above as a positive tonographic test. The ibopamine test performed on the following day was considered positive if there was an intraocular pressure (IOP) change of at least 3 mm Hg. Results: The sensitivity of the tonography and ibopamine tests was 69 and 53%, respectively, in eyes with OHT. The specificity of both tests was 97%. Although the sensitivity of the tonography test is higher than that of the ibopamine test, the difference between both was not statistically significant in these eyes ( p = 0.409). Positive results in tonography were associated with higher IOP, while the results were not dependent on the IOP in the ibopamine test. Both tests together were positive in 33.87% ( 21 eyes) and negative in 11.29% ( 7 eyes) in 62 eyes with OHT. Conclusion: This study revealed that the ibopamine provocation test can detect outflow system resistance in eyes with OHT comparable with tonography which is a traditional outflow facility measurement. Ibopamine, however, can detect the eye with outflow impairment by a different and IOP-independent way, while tonography depends on IOP. Copyright (C) 2005 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000082779
dc.identifier.endpage22en_US
dc.identifier.issn0030-3747
dc.identifier.issn1423-0259
dc.identifier.issue1en_US
dc.identifier.pmid15627837en_US
dc.identifier.scopus2-s2.0-18644367963en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage17en_US
dc.identifier.urihttps://doi.org/10.1159/000082779
dc.identifier.urihttps://hdl.handle.net/11616/93935
dc.identifier.volume37en_US
dc.identifier.wosWOS:000228663800004en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofOphthalmic Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectibopamine provocation testen_US
dc.subjecttonographyen_US
dc.subjectaqueous outflowen_US
dc.subjectocular hypertensionen_US
dc.titleThe comparison of topical ibopamine 2% with tonography to identify the outflow resistance in eyes with ocular hypertensionen_US
dc.typeArticleen_US

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