Response of antioxidant system to formalin in the whole body of rainbow trout, Oncorhynchus mykiss

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dc.authoridYonar, Serpil Mişe/0000-0003-2736-5731
dc.authoridYonar, Muhammet Enis/0000-0001-9519-4247
dc.authoridISPIR, UNAL/0000-0002-2077-0219
dc.authoridKIRICI, Muammer/0000-0003-1888-4388
dc.authorwosidIspir, Unal/JSK-1533-2023
dc.authorwosidYonar, Serpil Mişe/V-8276-2018
dc.authorwosidYonar, Muhammet Enis/V-8298-2018
dc.authorwosidKIRICI, Muammer/M-8355-2017
dc.contributor.authorIspir, U.
dc.contributor.authorKirici, M.
dc.contributor.authorYonar, M. E.
dc.contributor.authorYonar, S. Mise
dc.date.accessioned2024-08-04T20:43:01Z
dc.date.available2024-08-04T20:43:01Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractFormalin bath treatments are widely used to control of parasitic infections in aquaculture. However, effects of formaldehyde on the lipid peroxidation and antioxidant system were not still need elucidation. Fish were exposed to formalin at doses of 50, 100 and 200 ppm for 1 h. Fish were then left to depurate for 24 h in formalin-free water. At the end of the test, whole bodies were isolated and homogenized to measured malondialdehyde (MDA) and reduced glutathione (GSH) levels and catalase (CAT) and glutathione peroxidase (GPx) activities. Results obtained showed that formalin significantly (p < 0.05) increased the MDA level. There was statistically significant decrease in the CAT activity of the experimental groups when compared to the control group. After recovery period, the CAT activity was still found to be lower than the control level. The GPx activity and GSH level decreased by formalin exposures and did not return to the control values during recovery periods. From the findings of our study, it can be interpreted that acute formalin inhalation may cause oxidative stress and thus, some secondary toxic effects in whole body.en_US
dc.identifier.doi10.14715/cmb/2017.63.1.3
dc.identifier.endpage16en_US
dc.identifier.issn0145-5680
dc.identifier.issn1165-158X
dc.identifier.issue1en_US
dc.identifier.pmid28234619en_US
dc.identifier.scopus2-s2.0-85015351002en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage13en_US
dc.identifier.urihttps://doi.org/10.14715/cmb/2017.63.1.3
dc.identifier.urihttps://hdl.handle.net/11616/97731
dc.identifier.volume63en_US
dc.identifier.wosWOS:000397291600003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherC M B Assocen_US
dc.relation.ispartofCellular and Molecular Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFormalinen_US
dc.subjectRainbow trouten_US
dc.subjectOxidative stressen_US
dc.subjectAntioxidanten_US
dc.titleResponse of antioxidant system to formalin in the whole body of rainbow trout, Oncorhynchus mykissen_US
dc.typeArticleen_US

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