Interaction of nickel ferrite nanoparticles with nucleic acids

Basit Öğe Kaydı
dc.authoridTOPKAYA, SEDA NUR/0000-0002-7816-3155
dc.authoridKAYA, Hüseyin Oğuzhan/0000-0002-6529-8325
dc.authoridKARACA AÇARI, İDİL/0000-0001-6783-7030
dc.authoridCetin, Arif Engin/0000-0002-0788-8108;
dc.authorwosidTOPKAYA, SEDA NUR/GLT-5663-2022
dc.authorwosidKAYA, Hüseyin Oğuzhan/JTT-2031-2023
dc.authorwosidKARACA AÇARI, İDİL/AAB-2604-2022
dc.authorwosidCetin, Arif Engin/ABI-4321-2020
dc.authorwosidKARACA ACARİ, Idil/GVU-4371-2022
dc.contributor.authorTopkaya, Seda Nur
dc.contributor.authorAcari, Idil Karaca
dc.contributor.authorKaya, Huseyin Oguzhan
dc.contributor.authorOzcan, Imren
dc.contributor.authorKoytepe, Suleyman
dc.contributor.authorCetin, Arif E.
dc.date.accessioned2024-08-04T20:50:55Z
dc.date.available2024-08-04T20:50:55Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this article, we introduced an electrochemical biosensor employing graphite electrodes (GE) decorated with Nickel ferrite (NiFe2O4) nanoparticles for nucleic acid detection. NiFe2O4 nanoparticles in a narrow size distribution were synthesized with co-precipitation technique. Their chemical and crystallographic properties were characterized with FTIR and X-ray spectroscopies. Nanoparticle size distribution and hydrodynamic diameter were determined with particle size analyzer. Elemental content and purity of nanoparticles were analyzed with EDX analysis. Our analyses showed a diameter of similar to 10 nm for NiFe2O4 nanoparticles. Electrochemical properties of NiFe2O4 nanoparticles were examined with different analysis methods. Conductivity properties of NiFe2O4 nanoparticles were investigated with Cyclic Voltammetry (CV), which confirmed that nanoparticles on GE surface have a high surface area and conductivity. More importantly, in this article, the interactions between NiFe2O4 nanoparticles and double stranded DNA (dsDNA), single stranded DNA (ssDNA), and RNA were for the first time examined using Differential Pulse Voltammetry (DPV), CV, and Electrochemical Impedance Spectroscopy (EIS). Oxidation peak currents of NiFe2O4 nanoparticles and guanine bases of dsDNA, ssDNA, and RNA showed that NiFe2O4 nanoparticles effectively interacts with nucleic acids via an electrostatic mode.en_US
dc.identifier.doi10.1016/j.colsurfb.2021.112282
dc.identifier.issn0927-7765
dc.identifier.issn1873-4367
dc.identifier.pmid34915301en_US
dc.identifier.scopus2-s2.0-85121231324en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.colsurfb.2021.112282
dc.identifier.urihttps://hdl.handle.net/11616/100365
dc.identifier.volume211en_US
dc.identifier.wosWOS:000734888800005en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofColloids and Surfaces B-Biointerfacesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNickel ferriteen_US
dc.subjectNiFe2O4 nanoparticlesen_US
dc.subjectDifferential pulse voltammetryen_US
dc.subjectElectrochemical impedance spectroscopyen_US
dc.subjectCo-precipitationen_US
dc.titleInteraction of nickel ferrite nanoparticles with nucleic acidsen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu