Prognostic Value of Procalcitonin, CRP, Serum Amyloid A, Lactate and IL-6 Markers in Liver Transplant Patients Admitted to ED with Suspected Infection

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dc.authoridYucel, Neslihan/0000-0001-5845-2614
dc.authoridTurtay, Muhammet Gokhan/0000-0002-1728-8237
dc.authoridBayindir, Yasar/0000-0003-3930-774X
dc.authoridGurbuz, Sukru/0000-0003-2616-0304
dc.authoridErsan, Veysel/0000-0002-1510-0288
dc.authoridOguzturk, Hakan/0000-0002-9800-1428
dc.authoridKose, Adem/0000-0002-1853-1243
dc.authorwosidYucel, Neslihan/ABI-3412-2020
dc.authorwosidTurtay, Muhammet Gokhan/ABG-7401-2020
dc.authorwosidBayindir, Yasar/T-1523-2017
dc.authorwosidGurbuz, Sukru/ABI-3276-2020
dc.authorwosidErsan, Veysel/AAB-9595-2020
dc.authorwosidOguzturk, Hakan/AAC-3915-2021
dc.authorwosidGür, Ali/S-7601-2017
dc.contributor.authorGur, Ali
dc.contributor.authorOguzturk, Hakan
dc.contributor.authorKose, Adem
dc.contributor.authorTurtay, M. Gokhan
dc.contributor.authorErsan, Veysel
dc.contributor.authorBayindir, Yasar
dc.contributor.authorInce, Volkan
dc.date.accessioned2024-08-04T20:44:06Z
dc.date.available2024-08-04T20:44:06Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/Aim: Infections are one of the most important causes of mortality and morbidity after liver transplantation as in all transplantations. Infectious complications are known to be among the preventable causes with appropriate diagnosis and treatment. So early prediction of the risk of infections will provide an effective approach to determine the local antimicrobial resistance and prevention of specific risk factors. The aim of this study was to deterimne whether specific markers are useful or not to deterimne a suspected infection in patients that have undergone liver transplantation. Patients and Methods: The study included 65 patients with liver transplantation admitted to emergency room with suspicion of infection. These patient's CRP, procalsitonin (PCT), lactate, SAA and IL-6 levels were initially measured in the emergency department. The patients were classified to three categories according to culture results; culture-negative, culture-positive and control group. Studying parameters were investigated according to whether the culture was positive or negative in these patients. Results: CRP, PCT, lactate, SAA and IL-6 levels were significanlty high in patients with suspected infeciton when compared to the control group (p<0.05). CRP, PCT and IL-6 levels were higher in the culture-positive group than in the culture-negative group and there was a significant variation (p<0.05). When suspecting an infection evaluating the parameters CRP, PCT and IL-6 was very meaningfull (p<0.05). Conclusion: We can use CRP, PCT, lactate, SAA and IL-6 parameters to identify presence of infection at the liver transplantation patients admitted to the emergency department with suspected infection. If CRP, PCT and IL-6 levels are significantly high we can guess the patient's positive culture.en_US
dc.identifier.doi10.21873/invivo.11187
dc.identifier.endpage1185en_US
dc.identifier.issn0258-851X
dc.identifier.issn1791-7549
dc.identifier.issue6en_US
dc.identifier.pmid29102943en_US
dc.identifier.scopus2-s2.0-85033489140en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1179en_US
dc.identifier.urihttps://doi.org/10.21873/invivo.11187
dc.identifier.urihttps://hdl.handle.net/11616/98022
dc.identifier.volume31en_US
dc.identifier.wosWOS:000414546400020en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt Inst Anticancer Researchen_US
dc.relation.ispartofIn Vivoen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiver transplantationen_US
dc.subjectemergency departmenten_US
dc.subjectCRPen_US
dc.subjectPCTen_US
dc.subjectlactateen_US
dc.subjectSAAen_US
dc.subjectIL-6en_US
dc.titlePrognostic Value of Procalcitonin, CRP, Serum Amyloid A, Lactate and IL-6 Markers in Liver Transplant Patients Admitted to ED with Suspected Infectionen_US
dc.typeArticleen_US

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