Fibromyalji sendromlu hastalarda olaya ilişkin endojen potansiyeller (P300)
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Dosyalar
Tarih
2000
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Romatizma Dergisi (. Turkish Journal of Rheumatology)
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Öz: Fibromyalji, kronik kas iskelet sistemi ağrısı ve hassasiyeti ile karakterize non-artiküler romatizmal bir hastalıktır. Hastalarda dikkat, kısa süreli bellek ve uyku gibi bilişsel işlevlerde bozukluğa sıklıkla rastlanmaktadır. Olaya ilişkin endojen potansiyellerden P300 bilişsel işlevleri değerlendirmekte, demans ve Parkinson hastalığı gibi nörolojik hastalıkların yanısıra şizofreni ve depresyon gibi psikiyatrik hastalıklarda da uzun süredir kullanılan, uzun latanslı bir potansiyeldir. Bu çalışmada, Amerikan Romatoloji Koleji 1990 kriterlerine göre fibromyalji tanısı konan ve ilaç tedavisi başlanmamış 14 hasta ve hastalarla benzer yaş ve cinsiyet özellikleri gösteren 13 sağlıklı kontrol grubunda P300 potansiyeli çalışıldı. P300 yanıtı için hasta ve kontrollere işitsel şaşırtmalı uyaran (iki farklı tonda klik sesi) dizileri verildi. Fibromyaljili hastalardan elde edilen P300 potansiyellerinin ortalama latans (317.8±32.4 msn) ve ortalama amplitüd (12.9±7.8 mV) değerleri ile kontrol grubu ortalama latans (335.4±34.6 msn) ve ortalama amplitüd (12.9±6.8 mV) değerleri arasında istatiksel olarak (sırasıyla p=0.8 ve 0.9) fark bulunmadı.
Abstract: Fibromyalgia is a non-articular rheumatic disorder characterized by chronic widespread musculoskeletal pain and tenderness. Cognitive dysfunctions, especially difficulty in concentration, short term memory and sleep disturbances are also common in these patients. P300 being one of the event related endogen potential is used in the evaluation of the cognitive functions. It is a long latency potential used in some neurologic diseases such as dementia and Parkinson disease and also in psychiatric diseases such as schizophrenia and depression. In this study, we evaluated P300 potential in 14 patients diagnosed as fibromyalgia according to the American College of Rheumatology 1990 criteria. The control group included 13 healthy subjects. To test the P300 response, two different tones of click sound are given both patients and control group. There was no statistically significant difference between the average latency of P300 in the patients (317.8±32.4 ms) and controls (335.4±34.6 ms). In addition, no statistical difference was observed in the average amplitude of P300 in either group (12.9±7.8 mV, 12.9±6.8 mV, respectively).
Abstract: Fibromyalgia is a non-articular rheumatic disorder characterized by chronic widespread musculoskeletal pain and tenderness. Cognitive dysfunctions, especially difficulty in concentration, short term memory and sleep disturbances are also common in these patients. P300 being one of the event related endogen potential is used in the evaluation of the cognitive functions. It is a long latency potential used in some neurologic diseases such as dementia and Parkinson disease and also in psychiatric diseases such as schizophrenia and depression. In this study, we evaluated P300 potential in 14 patients diagnosed as fibromyalgia according to the American College of Rheumatology 1990 criteria. The control group included 13 healthy subjects. To test the P300 response, two different tones of click sound are given both patients and control group. There was no statistically significant difference between the average latency of P300 in the patients (317.8±32.4 ms) and controls (335.4±34.6 ms). In addition, no statistical difference was observed in the average amplitude of P300 in either group (12.9±7.8 mV, 12.9±6.8 mV, respectively).
Açıklama
Yıl: 2000Cilt: 15Sayı: 2ISSN: 1300-5286Sayfa Aralığı: 113 - 116Metin Dili:Türkçe
Anahtar Kelimeler
Kaynak
Romatizma Dergisi (. Turkish Journal of Rheumatology)
WoS Q Değeri
Scopus Q Değeri
Cilt
15
Sayı
2
Künye
BAYSAL Ö,ÖZCAN C,ERSOY Y,ALTAY E. Z (2000). Fibromyalji sendromlu hastalarda olaya ilişkin endojen potansiyeller (P300). Romatizma Dergisi (. Turkish Journal of Rheumatology), 15(2), 113 - 116.
