Bioactive contents, In vitro antiradical, antimicrobial and cytotoxic properties of rhubarb (Rheum ribes L.) extracts

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dc.authoridSandal, Suleyman/0000-0002-8916-3329
dc.authoridTekin, Suat/0000-0002-2757-1802
dc.authoridKaratepe, Mustafa/0000-0001-6358-5913
dc.authoridKaygili, Omer/0000-0002-2321-1455
dc.authoridKESER, Serhat/0000-0002-9678-1053
dc.authorwosidSandal, Suleyman/AAA-6388-2021
dc.authorwosidTekin, Suat/KEI-2266-2024
dc.authorwosidTurkoglu, İsmail/V-9145-2018
dc.authorwosidKaratepe, Mustafa/HII-5655-2022
dc.authorwosidTekin, Suat/IZD-9868-2023
dc.authorwosidTekin, Suat/AAG-1440-2021
dc.authorwosidKaygili, Omer/A-4801-2017
dc.contributor.authorKeser, Serhat
dc.contributor.authorKeser, Fatma
dc.contributor.authorKaratepe, Mustafa
dc.contributor.authorKaygili, Omer
dc.contributor.authorTekin, Suat
dc.contributor.authorTurkoglu, Ismail
dc.contributor.authorDemir, Ersin
dc.date.accessioned2024-08-04T20:45:41Z
dc.date.available2024-08-04T20:45:41Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractRheum ribes L. (rhubarb) is belonging to Polygonaceae, and its roots and fresh shoots are consumed as vegetable in Turkey. This plant is considered to be one of the most important pharmaceutical raw materials in Middle East. In this study, the antiradical, antimicrobial, cytotoxic and bioactive properties of water, ethanol, and methanol extracts of R. ribes stems were determined. R. ribes stems water, ethanol and methanol extracts are better scavenged ABTS(center dot+) (99.27, 99.91, and 99.88%), DPPH center dot (83.11, 81.42, and 83.26%), and OH center dot radicals (93.49, 94.21, 95.86%) than standard antioxidant BHA (95.32, 80.49, and 93.78%). Stems of R. ribes abundantly include bioactive compounds, dominated by rutin, catechin, caffeic acid, ferulic acid, alpha-tocopherol and vitamin D. These extracts show effective cytotoxic properties against PC-3, A2780, HCT-116 and MCF-7 cancer cell lines at 24h. It is found that R. ribes contain high amount important bioactive contents, and has effective antiradical and cytotoxic properties.en_US
dc.description.sponsorshipTUBITAK [115Z056]en_US
dc.description.sponsorship` This study was supported by TUBITAK, under grant number 115Z056.en_US
dc.identifier.doi10.1080/14786419.2018.1560294
dc.identifier.endpage3357en_US
dc.identifier.issn1478-6419
dc.identifier.issn1478-6427
dc.identifier.issue23en_US
dc.identifier.pmid30663386en_US
dc.identifier.scopus2-s2.0-85060347988en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage3353en_US
dc.identifier.urihttps://doi.org/10.1080/14786419.2018.1560294
dc.identifier.urihttps://hdl.handle.net/11616/98621
dc.identifier.volume34en_US
dc.identifier.wosWOS:000594432300006en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNatural Product Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRhubarben_US
dc.subjectantiradicalen_US
dc.subjectantimicrobialen_US
dc.subjectcytotoxicityen_US
dc.subjectphytosterolen_US
dc.titleBioactive contents, In vitro antiradical, antimicrobial and cytotoxic properties of rhubarb (Rheum ribes L.) extractsen_US
dc.typeArticleen_US

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