Evaluation of the effects of mono or combined use of topical antiglaucomatous drops on conjunctival flora and antibiotic susceptibility

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dc.authoridGündüz, Ayten/0000-0003-2031-9978
dc.authoridEkici gok, Zarife/0000-0002-9250-9618
dc.authorwosidGündüz, Ayten/HKO-6509-2023
dc.contributor.authorGok, Zarife Ekici
dc.contributor.authorGunduz, Ayten
dc.contributor.authorBozguel, Penpe Guel
dc.date.accessioned2024-08-04T20:54:56Z
dc.date.available2024-08-04T20:54:56Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: To evaluate the effects of mono or combined use of topical antiglaucomatous drops (AGD) on conjunctival flora and antibiotic susceptibility. Methods: The study group consisting of 84 glaucoma patients using AGDs and 32 healthy controls were evaluated. Groups were formed according to the use of 1, 2 and 3 AGDs. A swab was taken from the conjunctival sac from each patient and cultures were made. Patients with conjunctival hyperemia were classified according to their appearance. Results: The mean age was 58.61 +/- 14.55 years. Conjunctival culture positivity was 84.37%, 89.28% and 90.6% according to the use of 1, 2, and 3 AGDs, respectively, and it was 93.75% in the control group. Staphylococcus hominis (S. hominis) was statistically significantly higher in all glaucoma patients compared to healthy volunteers (p = .030). S. hominis was significantly higher especially in those using 2 (42.85%) and 3 (50%) AGDs, compared to those who received mono treatment (31.25%). Candida spp. was also significantly higher in glaucoma patients (p = .039). In patients with conjunctival hyperemia in glaucoma patients, the most common two bacteria were S. hominis (55.5%) and Staphylococcus epidermidis (S. epidermidis) (33%), respectively. In the relationship between isolated bacterial species and conjunctival hyperemia grades, Bacillus spp. (p = .013) was statistically significant. In glaucoma patients, norfloxacin and erythromycin resistance were found to be statistically significantly higher compared to the control group (p = .01). Conclusion: Considering the statistically significant increase in isolates in all glaucoma patients, we suggest that more care should be taken in terms of infection in surgical procedures planned for glaucoma patientsen_US
dc.identifier.doi10.1177/11206721231219275
dc.identifier.issn1120-6721
dc.identifier.issn1724-6016
dc.identifier.pmid38087444en_US
dc.identifier.scopus2-s2.0-85179650861en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1177/11206721231219275
dc.identifier.urihttps://hdl.handle.net/11616/101723
dc.identifier.wosWOS:001125828300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofEuropean Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlaucomaen_US
dc.subjectantiglaucomatous dropsen_US
dc.subjectconjunctival floraen_US
dc.subjectocular surface infectionen_US
dc.subjectantibiogramen_US
dc.titleEvaluation of the effects of mono or combined use of topical antiglaucomatous drops on conjunctival flora and antibiotic susceptibilityen_US
dc.typeArticleen_US

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