Can Preoperative Parameters of Inflammation be Used to Predict Acute Kidney Injury in Pediatric Liver Transplant Recipients? A Single-Center Retrospective Study

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dc.authoridDemiröz Tasolar, Sevgi/0000-0002-9836-6814
dc.authorwosidDemiröz Tasolar, Sevgi/KTI-6349-2024
dc.contributor.authorDemiroz, Duygu
dc.contributor.authorOzdes, Oya Olcay
dc.contributor.authorColak, Yusuf Ziya
dc.contributor.authorErdogan, Mehmet Ali
dc.contributor.authorGazioglu, Tugce
dc.contributor.authorKarakas, Serdar
dc.contributor.authorTasolar, Sevgi Demiroz
dc.date.accessioned2024-08-04T20:57:19Z
dc.date.available2024-08-04T20:57:19Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Inflammation is one of the factors involved in the occurrence and progression of acute kidney injury (AKI). We evaluated the relationship between preoperative systemic inflammatory markers and early postoperative AKI development in pediatric liver transplantation (LT) patients. Methods: Data from 190 pediatric patients were retrospectively analyzed. The preoperative neutrophil-to-lymphocyte ratio (NLR), systemic immune-inflammation index (SII), and pan-immune-inflammation value (PIV) levels were calculated. AKI was classified according to the Kidney Disease: Improving Global Outcomes staging. Patients who did not develop AKI in the early postoperative period were classified as group 0, patients with stage 1 AKI were classified as group 1, and patients with stage 2-3 AKI were classified as group 2. The relationship between the inflammatory parameters and AKI was evaluated. Results: AKI developed in 20% of patients, and 16.31% of these patients had severe AKI. The NLR, SII, and PIV values were significantly higher in patients with severe AKI (p<0.001). Preoperative high PIV values were found to be an independent predictor of AKI development. Conclusion: High preoperative PIV values may be used as a predictive factor for the development of early AKI in patients undergoing pediatric LT.en_US
dc.identifier.doi10.4274/imj.galenos.2024.92593
dc.identifier.endpage174en_US
dc.identifier.issn2619-9793
dc.identifier.issn2148-094X
dc.identifier.issue2en_US
dc.identifier.startpage170en_US
dc.identifier.urihttps://doi.org/10.4274/imj.galenos.2024.92593
dc.identifier.urihttps://hdl.handle.net/11616/102519
dc.identifier.volume25en_US
dc.identifier.wosWOS:001241475300015en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofIstanbul Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAcute kidney injuryen_US
dc.subjectpediatric transplantationen_US
dc.subjectsystemic immune inflammation indexen_US
dc.subjectpan-immune-inflammation valueen_US
dc.titleCan Preoperative Parameters of Inflammation be Used to Predict Acute Kidney Injury in Pediatric Liver Transplant Recipients? A Single-Center Retrospective Studyen_US
dc.typeArticleen_US

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