Placenta accreta risk-antepartum score in predicting clinical outcomes of placenta accreta spectrum: A multicenter validation study

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dc.authoridMELEKOGLU, RAUF/0000-0001-7113-6691
dc.authoridMakukhina, Tatiana/0000-0003-0536-4500
dc.authoridShazly, Sherif/0000-0003-1062-9227
dc.authoridElassall, Gena M./0000-0002-4460-1831
dc.authorwosidMELEKOGLU, RAUF/AAF-1614-2019
dc.authorwosidMakukhina, Tatiana/AAB-9292-2022
dc.contributor.authorShazly, Sherif A.
dc.contributor.authorAnan, Mohamed A.
dc.contributor.authorMakukhina, Tatiana B.
dc.contributor.authorMelekoglu, Rauf
dc.contributor.authorAhmed, Farhat Ul A.
dc.contributor.authorPinto, Pedro, V
dc.contributor.authorTakahashi, Hironori
dc.date.accessioned2024-08-04T20:50:52Z
dc.date.available2024-08-04T20:50:52Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective To validate the use of placenta accreta risk-antepartum (PAR-A) score as a predictive tool of clinical outcomes of placenta accreta spectrum (PAS). Methods This is a prospective study, conducted in six PAS specialized centers in six different countries. The study was conducted between October 1, 2020 and March 31, 2021. Women who were provisionally diagnosed with PAS during pregnancy were considered eligible. A machine-learning-based PAR-A score was calculated. Diagnostic performance of the PAR-A score was evaluated using a receiver operating characteristic curve, for perioperative massive blood loss and admission to intensive care unit (ClinicalTrials.gov identifier NCT04525001). Results Of 97 eligible women, 86 were included. PAS-associated massive blood loss occurred in 10 patients (11.63%). Median PAR-A scores of massive blood loss in the current cohort were 8.9 (interquartile range 6.9-14.1). In predicting massive blood loss, the area under the curve of PAR-A scores was 0.85 (95% confidence interval [CI] 0.74-0.95), which was not significantly different from the original cohort (P = 0.2). PAR-A score prediction of intensive care unit admission was slightly higher compared with the original cohort (0.88, 95% CI 0.81-0.95; P = 0.06). Conclusion PAR-A score is a novel scoring system of PAS outcomes, which showed external validity based on current data.en_US
dc.identifier.doi10.1002/ijgo.13993
dc.identifier.endpage431en_US
dc.identifier.issn0020-7292
dc.identifier.issn1879-3479
dc.identifier.issue2en_US
dc.identifier.pmid34674270en_US
dc.identifier.scopus2-s2.0-85119290152en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage424en_US
dc.identifier.urihttps://doi.org/10.1002/ijgo.13993
dc.identifier.urihttps://hdl.handle.net/11616/100313
dc.identifier.volume158en_US
dc.identifier.wosWOS:000718258000001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Gynecology & Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmachine learningen_US
dc.subjectobstetric emergencyen_US
dc.subjectobstetric hemorrhageen_US
dc.subjectplacenta previaen_US
dc.subjectplacental morbidityen_US
dc.subjectrisk stratificationen_US
dc.titlePlacenta accreta risk-antepartum score in predicting clinical outcomes of placenta accreta spectrum: A multicenter validation studyen_US
dc.typeArticleen_US

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