Comparison of cardiovascular effects and intubating conditions of cisatracurium and rocuronium in patients with coronary artery disease

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dc.authorscopusid7801337882
dc.authorscopusid8932188900
dc.authorscopusid6603851680
dc.authorscopusid7004839297
dc.authorscopusid6701613323
dc.authorscopusid7004486274
dc.contributor.authorTorkoz A.
dc.contributor.authorBut A.K.
dc.contributor.authorKoroglu A.
dc.contributor.authorDurmus M.
dc.contributor.authorTogal T.
dc.contributor.authorErsoy M.O.
dc.date.accessioned2024-08-04T20:00:36Z
dc.date.available2024-08-04T20:00:36Z
dc.date.issued2000
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study was designed to compare the cardiovascular effects and intubation condition of cisatracurium and rocuronium in cardiac surgical patients. Twenty patients scheduled for elective coronary artery bypass surgery were randomly assigned into two equal groups in a double blind fashion. Patients in group R (n=10) were given 0.9 mg/kg rocuronium and patients in group C (n=10) were given 0.15 mg/kg cisatracurium. Tracheal intubation was performed upon completion of maximum depression (% 100) in Train-of-four stimulation. Intubation conditions were rated according to Goldberg scale [1 (excellent) to 4 (intubation not possible)]. Heart rate (HR), systolic and diastolic arterial pressure SAP and DAP), central venous pressure (CVP), mean pulmonary artery pressure (PAPm), pulmonary artery wedge pressure (PAWP), cardiac output (CO), cardiac index (CI), systemic and pulmonary vascular resistances (SVR and PVR) were measured invasively. Measurements were made before induction, 2 min after induction of anesthesia (basal), 1 min after after administration of muscle relaxant, at maximum depression in TOF and 2, 5, 10 min after intubation. Intubation condition were excellent in 60% of patients in the rocuronium group and in 90% of patients in the cisatracurium group, however there were no significant differences between the two groups (p>0.05). Rocuronium produced statistically significant increase in the heart rate at maximum depression in TOF, 2 min after intubation and in systolic blood pressure at 2 min after intubation (p<0.05). Other hemodynamic changes (DBP, CVP, CO, CI, PAPm, PAWP, SVR, PVR) were similar in the groups. As a result, induction with cisatracurium presented a more haemodynamically stable situation than rocuronium, but increases of cardiac rate and blood pressure with rocuronium were within clinically acceptable values.en_US
dc.identifier.endpage230en_US
dc.identifier.issn1016-5150
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-0034041475en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage226en_US
dc.identifier.urihttps://hdl.handle.net/11616/90842
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCisatracuriumen_US
dc.subjectHaemodynamic effecten_US
dc.subjectIntubationen_US
dc.subjectRocuroniumen_US
dc.titleComparison of cardiovascular effects and intubating conditions of cisatracurium and rocuronium in patients with coronary artery diseaseen_US
dc.title.alternativeKoroner arter hastalarinda rokuronyum ve cisatrakuryum'un entubasyon kosullari ve kardiyovaskuler sisteme etkisien_US
dc.typeArticleen_US

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