Is airborne transmission of Acinetobacter baumannii possible A prospective molecular epidemiologic study in a tertiary care hospital

dc.authorid101949en_US
dc.contributor.authorYakupoğulları, Yusuf
dc.contributor.authorOtlu, Barış
dc.contributor.authorErsoy, Yasemin
dc.contributor.authorKuzucu, Çiğdem
dc.contributor.authorBayındır, Yaşar
dc.contributor.authorKayabaş, Üner
dc.contributor.authorTogal, Türkan
dc.contributor.authorKızılkaya, Canan
dc.date.accessioned2017-07-10T07:40:27Z
dc.date.available2017-07-10T07:40:27Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Understanding the dynamics of aerial spread of Acinetobacter may provide useful information for production of effective control measurements. We investigated genetic relationships between air and clinical isolates of Acinetobacter baumannii in an intensive care unit (ICU) setting. Methods: We conducted a prospective surveillance study in a tertiary care hospital for 8 months. A total of 186 air samples were taken from 2 ICUs. Clonal characteristics of air isolates were compared with the prospective clinical strains and the previously isolated strains of ICU patients over a 23-month period. Results: Twenty-six (11.4%) air samples yielded A baumannii, of which 24 (92.3%) isolates were carbapenemresistant. The Acinetobacter concentration was the highest in bedside sampling areas of infected patients (0.39 CFU/ m3). Air isolates were clustered in 13 genotypes, and 7 genotypes (including 18 air strains) were clonally related to the clinical strains of 9 ICU patients. One clone continued to be cultured over 27 days in ICU air, and air isolates could be clonally related to 7-week retrospective and approximately 15-week prospective clinical strains. Conclusions: The results of this study suggest that infected patients could spread significant amounts of Acinetobacter to ICU air. These strains could survive in air for some weeks and could likely still infect new patients after some months. Special control measurements may be required against the airborne spread of Acinetobacter in ICUs.en_US
dc.identifier.citationYakupoğulları, Y. Otlu, B. Ersoy, Y. Kuzucu, Ç. Bayındır, Y. Kayabaş, Ü. Togal, T. Kızılkaya, C. (2016). s airborne transmission of Acinetobacter baumannii possible A prospective molecular epidemiologic study in a tertiary care hospital. American Journal of Infection Control, 44(12), 1595–1599.en_US
dc.identifier.doi10.1016/j.ajic.2016.05.022en_US
dc.identifier.endpage1599en_US
dc.identifier.issn01966553
dc.identifier.issue12en_US
dc.identifier.startpage1595en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S0196655316306162
dc.identifier.urihttps://hdl.handle.net/11616/7352
dc.identifier.volume44en_US
dc.language.isoenen_US
dc.publisherAmerican Journal of Infection Controlen_US
dc.relation.ispartofAmerican Journal of Infection Controlen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIntensive care uniten_US
dc.subjectHealth care-associated infectionen_US
dc.subjectAerial spreaden_US
dc.subjectEnvironmental samplingen_US
dc.titleIs airborne transmission of Acinetobacter baumannii possible A prospective molecular epidemiologic study in a tertiary care hospitalen_US
dc.typeArticleen_US

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