Detection of the regression on hydroxychloroquine retinopathy in optical coherence tomography

dc.authoridTurgut, Burak/0000-0002-5393-0557
dc.authoridturkcuoglu, peykan/0000-0002-9750-6213
dc.authorwosidturkcuoglu, peykan/GQB-2596-2022
dc.authorwosidTurgut, Burak/K-8932-2014
dc.contributor.authorTurgut, Burak
dc.contributor.authorTurkcuoglu, Peykan
dc.contributor.authorKoca, Suleyman Serdar
dc.contributor.authorAydemir, Orhan
dc.date.accessioned2024-08-04T20:31:11Z
dc.date.available2024-08-04T20:31:11Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractHydroxychloroquine (HCQ) that is widely used in the treatment of the connective tissue disorders can cause retinopathy. The fundus examination of a patient with systemic lupus erythematosus receiving HCQ revealed left incomplete bull's eye and pigmentary changes in macula in the right eye. Repeated visual field tests showed the paracentral and peripheral defects in the right eye and the pericentral ring scotoma in the left eye. Optical coherence tomography (OCT) scans revealed the photoreceptor loss, retina pigment epithelium (RPE) irregularities, and a cyst-like hypo reflective space over RPE layer on the nasal perifoveal region in the left eye. On the ophthalmoscopic examination, the perifoveal pigmentation was not altered after the discontinuation of HCQ. However, the bilateral visual field defects were improved and the photoreceptor destruction and cyst-like hyporeflective space disappeared in the left eye. Mild RPE irregularities remained in both eyes as revealed by OCT scans. Even if OCT is used to evaluate the regression of HCQ retinopathy, it only shows advanced stage of retinopathy.en_US
dc.identifier.doi10.1007/s10067-009-1108-0
dc.identifier.endpage609en_US
dc.identifier.issn0770-3198
dc.identifier.issue5en_US
dc.identifier.pmid19221829en_US
dc.identifier.scopus2-s2.0-64449087085en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage607en_US
dc.identifier.urihttps://doi.org/10.1007/s10067-009-1108-0
dc.identifier.urihttps://hdl.handle.net/11616/94785
dc.identifier.volume28en_US
dc.identifier.wosWOS:000264879200020en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofClinical Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHydroxychloroquine retinopathyen_US
dc.subjectOptical coherence tomographyen_US
dc.subjectSystemic lupus erythematosusen_US
dc.titleDetection of the regression on hydroxychloroquine retinopathy in optical coherence tomographyen_US
dc.typeArticleen_US

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