Primary Hepatic Actinomycosis Mimicking Neuroendocrine Tumor

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dc.authoridOzdemir, Fatih/0000-0003-0292-3602
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authorwosidOzdemir, Fatih/ABH-2875-2020
dc.authorwosidSARICI, KEMAL BARIŞ/ABI-4356-2020
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.contributor.authorKaplan, Kuntay
dc.contributor.authorSarici, Kemal Baris
dc.contributor.authorUsta, Sertac
dc.contributor.authorozdemir, Fatih
dc.contributor.authorIsik, Burak
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:51:41Z
dc.date.available2024-08-04T20:51:41Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction The Actinomyces species is a fastidious, gram-positive, non-spore-forming bacteria that thrive in microareophilic and anaerobic conditions. Infection in the liver, an organ rarely affected by this pathogen, is presumed to be caused by hematogenous spread through the portal vein from a mucosal injury or other abdominal injury or a focus of infection. Case Description A 60-year-old male patient has a mass lesion of 15 x 10 cm in the left lobe on computed tomography. A tru-cut biopsy was performed with USG, and fragmented tissue pieces were obtained. In histopathological examination, these samples were reported as tumors with neuroendocrine differentiation. The biopsy sample contains a large amount of tumor neighborhood, and tumoral area is quite small. And, therefore, a clear diagnosis could not be found. A mass lesion with mildly increased Ga 68 DOTATATE uptake was observed in the left lobe of the liver (SUVmax value 3.8) and was interpreted in favor of the primary neuroendocrine tumor of the liver. Discussion Actinomyces cases are very rare and their diagnosis is usually delayed due to its slow and insidious course, and lack of specific clinical and radiological findings. It is difficult to make a correct diagnosis even in microbiological examinations and biopsy materials obtained in the presence of imaging methods. It can mimic tumors of abdominopelvic structures. Conclusion Actinomyces should be kept in mind in cases with liver masses accompanied by previous abdominal surgery, abdominal trauma, high fever, and leukocytosis.en_US
dc.identifier.doi10.1007/s12029-022-00806-2
dc.identifier.endpage296en_US
dc.identifier.issn1941-6628
dc.identifier.issn1941-6636
dc.identifier.issue1en_US
dc.identifier.pmid35184235en_US
dc.identifier.scopus2-s2.0-85124721999en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage294en_US
dc.identifier.urihttps://doi.org/10.1007/s12029-022-00806-2
dc.identifier.urihttps://hdl.handle.net/11616/100489
dc.identifier.volume54en_US
dc.identifier.wosWOS:000757919900001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Gastrointestinal Canceren_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectActinomycesen_US
dc.subjectNeuroendocrineen_US
dc.subjectHepaticen_US
dc.titlePrimary Hepatic Actinomycosis Mimicking Neuroendocrine Tumoren_US
dc.typeArticleen_US

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