Diffusion-weighted magnetic resonance imaging and magnetic resonance spectroscopy features of abdominal viscera in a patient with Gaucher's disease

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dc.authorscopusid56070200500
dc.authorscopusid8405312500
dc.authorscopusid7003405757
dc.authorscopusid53870177700
dc.authorscopusid7006266098
dc.contributor.authorKalayci T.O.
dc.contributor.authorErdem G.
dc.contributor.authorKutlu R.
dc.contributor.authorKahraman A.
dc.contributor.authorAlkan A.
dc.date.accessioned2024-08-04T20:02:21Z
dc.date.available2024-08-04T20:02:21Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA 46-year-old woman with Gaucher's disease (GD) consulted our clinic for abdominopelvic magnetic resonance imaging (MRI), as physical examination had revealed hepatosplenomegaly. Upper abdominal MRI showed massive hepatosplenomegaly and innumerable hypointense splenic nodules on T1-weighted images. Diffusion-weighted MRI (DW-MRI) and magnetic resonance spectroscopy (MRS) were performed to liver parenchyma and splenic nodules. MRS revealed lactate, lipid, acetate, and alanine peaks in splenic nodules, and choline, creatine, lipid, myo-inositol-glycine, and lactate peaks in the liver parenchyma. The DW-MRI showed diffusion restriction in splenic nodules. It was concluded that MRI is a reliable method for the diagnosis and follow up of GD. Coupling DW-MRI and MRS allows quantitative evaluation, thereby increasing the efficacy of the method. This is the first report in the literature presenting advanced abdominal MRI findings in GD. © Penerbit Universiti Sains Malaysia, 2014.en_US
dc.identifier.endpage93en_US
dc.identifier.issn1394-195X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84902367932en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://hdl.handle.net/11616/91630
dc.identifier.volume21en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMalaysian Journal of Medical Sciencesen_US
dc.relation.ispartofMalaysian Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiffusion magnetic resonance imagingen_US
dc.subjectGaucher diseaseen_US
dc.subjectMagnetic resonance spectroscopyen_US
dc.titleDiffusion-weighted magnetic resonance imaging and magnetic resonance spectroscopy features of abdominal viscera in a patient with Gaucher's diseaseen_US
dc.typeArticleen_US

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