The effect of low-dose ketamine on ephedrine requirement following spinal anesthesia in cesarean sections: a randomised controlled trial

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dc.authoridOZGUL, Ulku/0000-0003-3738-1751
dc.authoridGulhas, Nurcin/0000-0002-2539-9017
dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridErdil, Feray Akgül/0000-0002-7544-3717
dc.authoridSanli, Mukadder/0000-0003-1009-5536
dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authorwosidOZGUL, Ulku/ABI-6823-2020
dc.authorwosidGulhas, Nurcin/A-7281-2018
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidErdil, Feray Akgül/ABI-2474-2020
dc.authorwosidSanli, Mukadder/ABI-8124-2020
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.contributor.authorGulhas, Nurcin
dc.contributor.authorOzgul, Ulku
dc.contributor.authorErdil, Feray
dc.contributor.authorSanli, Mukadder
dc.contributor.authorNakir, Hamza
dc.contributor.authorYologlu, Saim
dc.contributor.authorDurmus, Mahmut
dc.date.accessioned2024-08-04T20:36:11Z
dc.date.available2024-08-04T20:36:11Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: We aimed to assess the effectiveness of subanesthetic doses of ketamine on ephedrine requirement in patients scheduled for Cesarean section under spinal anesthesia. Methods: ASA I-II, 105, patients were enrolled in the study. Spinal anesthesia was achieved with 12.5 mg hyperbaric bupivacaine and 15 mu g fentanyl. Following spinal anesthesia, patients were randomly allocated to three groups. Group Placebo: 2 mL of intravenous physiological saline, Group Ketamine 0.25: 0.25 mg.kg(-1) of intravenous ketamine, and Group Ketamine 0.5: 0.5 mg.kg(-1) of intravenous ketamine was received. Results: The systolic and mean blood pressures were similar in the groups. There were no significant differences between the groups, number of hypotensive attacks, as well as the amount of ephedrine used. The sedation scores in Group Ketamine 0.25 and Group Ketamine 0.5 were significantly higher than Group Placebo (p=0.001) Conclusions: Subanesthetic dose of ketamine is not effective on decreasing ephedrine requirement in Cesarean section under spinal anesthesia.en_US
dc.identifier.endpage2876en_US
dc.identifier.issn1840-2291
dc.identifier.issn1986-8103
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-84868143076en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage2870en_US
dc.identifier.urihttps://hdl.handle.net/11616/95840
dc.identifier.volume6en_US
dc.identifier.wosWOS:000310816500037en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDrunpp-Sarajevoen_US
dc.relation.ispartofHealthmeden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectketamineen_US
dc.subjectmaternal hypotensionen_US
dc.subjectspinal anesthesiaen_US
dc.subjectCesarean sectionen_US
dc.titleThe effect of low-dose ketamine on ephedrine requirement following spinal anesthesia in cesarean sections: a randomised controlled trialen_US
dc.typeArticleen_US

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