What should be the minimum frequency of micro testicular sperm extraction (m-TESE) in patients with Klinefelter syndrome?
| dc.contributor.author | Salvarci, Ahmet | |
| dc.contributor.author | Balasar, Mehmet | |
| dc.date.accessioned | 2022-03-08T09:25:33Z | |
| dc.date.available | 2022-03-08T09:25:33Z | |
| dc.date.issued | 2019 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: To investigate whether a second or even a third surgery is required for sperm retrieval in non-mosaic Klinefelter syndrome patients who underwent a successful/failed micro-testicular sperm extraction (m-TESE).Material and Methods: The patients underwent physical examination, genetic analyses, pathological screening between 2008 and 2018. In the patients, sperm retrieval rates, pregnancy after intracytoplasmic sperm injection (ICSI) and baby take-home rates were examined.Results: M-TESE was repeated for the second time in thirty-five patients in total, with twenty of that underwent their first m-TESE with a negative result and fifteen with a positive result. In =6/20 patients (30%) who had a negative result with the first m-TESE and in n=9/15 patients (60%) who had a positive result with the first m-TESE, sperm was detected the second time. Pregnancy was achieved in n=2/6 patients (33%) who were negative the first time and positive the second time. Baby take-home was achieved in one patient (16.6%). Conclusion: In addition to patients from whom sperm could be retrieved previously, sperm could be detected especially in the second and even third redo m-TESE in patients from whom sperm could not be retrieved. Pregnancy occurred and baby take-home was achieved. Despite the presence of a very limited testicular tissue, it is recommended for this procedure to be performed by expert practitioners upon discussing very openly the complications and achievements, to decide accordingly and repeat m-TESE in these patients where possible. | en_US |
| dc.identifier.citation | Salvarci, A., & Balasar, M. (2021). What should be the minimum frequency of micro testicular sperm extraction (m-TESE) in patients with Klinefelter syndrome? . Annals of Medical Research, | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/54723 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | What should be the minimum frequency of micro testicular sperm extraction (m-TESE) in patients with Klinefelter syndrome? | en_US |
| dc.type | Article | en_US |
