Effect of abdominal insufflation on bacterial growth in experimental peritonitis

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dc.contributor.authorSare, M
dc.contributor.authorDemirkiran, AE
dc.contributor.authorAlibey, E
dc.contributor.authorDurmaz, B
dc.date.accessioned2024-08-04T20:12:12Z
dc.date.available2024-08-04T20:12:12Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Perforated appendicitis can be treated laparoscopically, but this approach is associated with a higher rate of intra-abdominal abscess. Pneumoperitoneum impairs the clearance of bacteria from the peritoneal cavity in experimental models of peritonitis. The aim of this study was to investigate the effects of intra-abdominal gas insufflation on bacterial growth in a rat model. Materials and Methods: The effects of intraperitoneal insufflation with different gases and a gasless model on bacterial proliferation in a setting of Escherichia coli-induced experimental peritonitis were studied in a rat model. Saline (0.25 mL) was given intraperitoneally to six Wistar male rats as the sham group. Escherichia coli (1.5 x 10(9) cfu/mL per kilogram) was injected intraperitoneally into to 24 rats. Microorganism counts were taken after 8 hours, and rats were divided into three groups: group 1, CO2 insufflation; group 2, N2O insufflation; and group 3, no insufflation. Microorganism counts were repeated 8 hours after the procedure (at 16 hours postinjection). Results: The difference in microorganism counts between 8 and 16 hours were significant in the CO2 and N2O insufflation groups (P < 0.05) but not in the group without pneumoperitoneum. Conclusions: Abdominal insufflation may promote intra-abdominal bacterial growth or decrease intra-abdominal bacterial clearance.en_US
dc.identifier.doi10.1089/109264201317054573
dc.identifier.endpage289en_US
dc.identifier.issn1092-6429
dc.identifier.issue5en_US
dc.identifier.pmid11642664en_US
dc.identifier.scopus2-s2.0-0034788363en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage285en_US
dc.identifier.urihttps://doi.org/10.1089/109264201317054573
dc.identifier.urihttps://hdl.handle.net/11616/93283
dc.identifier.volume11en_US
dc.identifier.wosWOS:000171467100004en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMary Ann Liebert Inc Publen_US
dc.relation.ispartofJournal of Laparoendoscopic & Advanced Surgical Techniques-Part Aen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOpen Appendectomyen_US
dc.subjectPneumoperitoneumen_US
dc.subjectModelen_US
dc.subjectAppendicitisen_US
dc.subjectBacteremiaen_US
dc.titleEffect of abdominal insufflation on bacterial growth in experimental peritonitisen_US
dc.typeArticleen_US

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