Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience

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dc.contributor.authorVarol, Fatma Ilknur
dc.contributor.authorGungor, Sukru
dc.contributor.authorSelimoglu, Mukadder Ayse
dc.contributor.authorSamdanci, Emine
dc.date.accessioned2024-08-04T20:55:00Z
dc.date.available2024-08-04T20:55:00Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/Aims: Solitary rectal ulcer syndrome (SRUS) can be overlooked, diagnosed late, or misdiagnosed, particularly in childhood. This study reviewed the 13-year experience of the authors' institution to increase clinicians' awareness of SRUS in the presence of symptoms. This paper reports the endoscopic and histopathological findings in children presenting with hematochezia. Methods: The clinical and laboratory findings of 22 patients diagnosed with biopsy-proven SRUS in the authors' clinic between 2007 and 2020 were evaluated retrospectively. Results: The mean age at diagnosis was 12.5 +/- 2.6 years, and 59.1% of the patients were male. The median time of diagnosis was 24 months. A single ulcer lesion was found by colonoscopy in 18 patients (81.8%), two ulcers in two patients (9%), and more than two ulcers in two patients (9%). The pathology reports of all biopsies taken from the lesions were consistent with a solitary rectal ulcer. In the first stage, the treatment was started with toilet training, a high-fiber diet, and laxatives. In 11 patients (50%) who did not respond to the initial treatment, a 5-ASA enema was added. A glucocorticoid enema was added to treatment in five patients (22%) whose complaints did not regress despite this treatment. Clinical remission was achieved in five of the patients (18.1%). The time to diagnosis was significantly shorter in those in remission than those not in remission (p=0.04). Conclusions: This study is the first large series on Turkish children. An increased awareness of SRUS in children will increase the rate of early diagnosis and treatment, allowing remission in more patients.en_US
dc.identifier.doi10.4166/kjg.2023.093
dc.identifier.endpage22en_US
dc.identifier.issn1598-9992
dc.identifier.issn2233-6869
dc.identifier.issue1en_US
dc.identifier.pmid38268164en_US
dc.identifier.scopus2-s2.0-85183335899en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage17en_US
dc.identifier.urihttps://doi.org/10.4166/kjg.2023.093
dc.identifier.urihttps://hdl.handle.net/11616/101781
dc.identifier.volume83en_US
dc.identifier.wosWOS:001205427200003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKorean Soc Gastroenterologyen_US
dc.relation.ispartofKorean Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChildrenen_US
dc.subjectHematocheziaen_US
dc.subjectSolitaryen_US
dc.subjectRectalen_US
dc.subjectUlceren_US
dc.titleRare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experienceen_US
dc.typeArticleen_US

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