Genotype distribution in Hepatitis C patients admitted to Erzincan Mengücek Gazi Training and Research Hospital

dc.contributor.authorYılmaz, Aysun
dc.contributor.authorKara, Murat
dc.contributor.authorKarakeçili, Faruk
dc.contributor.authorDabanlıoğlu, Bülent
dc.contributor.authorArslan, Yusuf Kemal
dc.date.accessioned2021-03-24T08:05:11Z
dc.date.available2021-03-24T08:05:11Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAbstract: Aim: We aimed to determine the genotype distribution in Hepatitis C patients who Parasitology applied to Erzincan Binali Yildirim University, Mengücek Gazi Training and Research Hospital. Hepatitis C virus, the only member of the genus Hepacivirus of Flaviviridae family, is responsible for 25%-40% of all liver diseases. Hepatitis C virus causes acute hepatitis C and chronic hepatitis C infections. Chronic hepatitis C infection causes cirrhosis, liver failure, hepatocellular cancerand liver diseases in terminal periods. Material and Methods: A total of 77 patients, 41 male and 36 female, who were admitted to Erzincan Binali Yıldırım University, Mengücek Gazi Training and Research Hospital in the period of January 2013-June 2019, were included in our study. RT-PCR and DNA sequencing for the 5’UTR region of the HCV genome for HCV genotyping was performed using the ABI Prism 3130 × 1 DNA Sequencer device. Results: Sex of a total of 77 patients included in the study; 41 of them are men (53.2%) and 36 are women (46.8%). Average age of the patients; It was 59.9 ± 16.6 (minimum 20 and maximum 94). HCV G1b (80.5%) in 62 patients, HCV G1a (7.8%) in 6, HCV G3a (3.9%) in 3, HCV G3 (2.6%) in 2 and HCV G2 (2.6%) was found in 2 patients. HCV G1 (1.3%) was detected in 1, HCV G4 (1.3%) in 1 patient. Conclusion: The dominant genotype in Hepatitis C patients who applied to Mengücek Gazi Training and Research Hospital was determined as “HCV Genotype 1b”.en_US
dc.identifier.citationYILMAZ A,KARA M,KARAKEÇİLİ F,DABANLIOĞLU B,ARSLAN Y. K (2020). Genotype distribution in Hepatitis C patients admitted to Erzincan Mengücek Gazi Training and Research Hospital. Annals of Medical Research, 27(5), 1369 - 1373. Doi: 10.5455/annalsmedres.2020.03.265en_US
dc.identifier.doi10.5455/annalsmedres.2020.03.265en_US
dc.identifier.endpage1373en_US
dc.identifier.issn2636-7688
dc.identifier.issue5en_US
dc.identifier.startpage1369en_US
dc.identifier.trdizinid361388en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2020.03.265
dc.identifier.urihttps://hdl.handle.net/11616/19712
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/361388
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleGenotype distribution in Hepatitis C patients admitted to Erzincan Mengücek Gazi Training and Research Hospitalen_US
dc.typeArticleen_US

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