Assessment of ventricular repolarization in deaf-mute children

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dc.authoridPekdemir, Hasan/0000-0002-4913-5120;
dc.authorwosidPekdemir, Hasan/ABI-6096-2020
dc.authorwosidGüven, Aytekin/AAJ-8546-2021
dc.contributor.authorTuncer, C
dc.contributor.authorÇokkeser, Y
dc.contributor.authorKomsuoglu, B
dc.contributor.authorÖdemir, R
dc.contributor.authorGüven, A
dc.contributor.authorPekdemir, H
dc.contributor.authorSezgin, AT
dc.date.accessioned2024-08-04T20:12:09Z
dc.date.available2024-08-04T20:12:09Z
dc.date.issued2000
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe long QT syndrome is a congenital disease with frequent familial transmission, characterized primarily by prolongation of the QT interval and by the occurrence of life-threatening arrhythmias. The syndrome may be familial, with or without congenital deafness, or it may be idiopathic. We attempted to assess ventricular repolarization and to identify patients with the Jervell and Lange-Nielsen syndrome among 132 deaf-mute school children. Five deaf-mute subjects had Jervell and Lange-Nielsen syndrome. The deaf-mute subjects were divided into two subgroups according to the length of their QT intervals: group 1 included 5 cases with the long QT interval (>440 msec), and group 2 included 127 subjects with the normal QT interval (less than or equal to 440 msec). Group 3 was composed of 96 control subjects. The mean QT, QTc, JT, and JTc intervals (418 +/- 70, 500 +/- 38, 302 +/- 65, and 389 +/- 36 msec, respectively) in group 1 were significantly longer than those of group 2 (344 +/- 23, 408 +/- 22, 249 +/- 34, and 291 +/- 28 msec, respectively) and group 3 (325 +/- Il, 383 +/- 26, 228 +/- 36, and 269 +/- 46 msec, respectively). The dispersion (d) values (QT-d, QTc-d, JT-d, and JTc-d; 63 +/- 10, 73 +/- 8, 60 +/- 8, and 62 +/- Il msec, respectively) of group 1 were significantly longer than those of group 2 (49 +/- 16, 43 +/- 11, 48 +/- 21, and 45 +/- 18 msec, respectively) and group 3 (33 +/- 13, 33 +/- 14, 28 +/- 16, and 27 +/- 14 msec, respectively) at similar mean RR intervals. Also, the mean QT, QTc, JT, and JTc intervals and the dispersion values (QT-d, QTc-d, JT-d, and JTc-d) in group 2 were significantly longer than those of group 3 at similar mean RR intervals. Consequently, in this study, we determined that the deaf-mute children who did not meet the criteria for Jervell and Lange-Nielsen syndrome still had evidence of subtle derepolarization abnormalities evidenced by intermediate prolongation of QTc, JTc, and the corresponding measures of dispersion, and we believe an electrocardiogram examination of deaf-mute subjects will reveal this potentially life-threatening syndrome.en_US
dc.identifier.doi10.1007/s002469910021
dc.identifier.endpage140en_US
dc.identifier.issn0172-0643
dc.identifier.issn1432-1971
dc.identifier.issue2en_US
dc.identifier.pmid10754083en_US
dc.identifier.scopus2-s2.0-0034096696en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage135en_US
dc.identifier.urihttps://doi.org/10.1007/s002469910021
dc.identifier.urihttps://hdl.handle.net/11616/93257
dc.identifier.volume21en_US
dc.identifier.wosWOS:000086244300007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofPediatric Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectlong QTen_US
dc.subjectrepolarizationen_US
dc.subjectdispersionen_US
dc.subjectdeafnessen_US
dc.subjectelectrocardiographyen_US
dc.titleAssessment of ventricular repolarization in deaf-mute childrenen_US
dc.typeArticleen_US

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