The humoral immun response of mice to liposomes containing Brucella melitensis outer membrane fragments
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Brucellosis is an important zoonotic disease and the prevention is made by vaccination of animals. For ewes Brucella melitensis REV-1 live attenuated vaccine is widely used but because of some risks such as being infected during the vaccination, re-infection of animals, a new vaccine with less side effect is need to be improved. In this study it was aimed to determine a strong humoral immune response by encapsulating the Brucella outer membrane antigens with the optimum liposome formulation and the statistical analyses showed that the Brucella outer membrane extract encapsulated with liposome can evoke humoral immune response better than live attenuated B. melitensis REV-1 vaccine in mice. © Medwell Journals, 2008.
Açıklama
Anahtar Kelimeler
Brucella, Humoral immunity, Liposomes, Vaccine
Kaynak
Journal of Animal and Veterinary Advances
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
7
Sayı
8
