A detailed analysis of surgical site infections and risk factors: A multicentric cohort study in Türkiye

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dc.authorscopusid26031949600
dc.authorscopusid17134524000
dc.authorscopusid57208259946
dc.authorscopusid37037560900
dc.authorscopusid17434860000
dc.authorscopusid59205470500
dc.authorscopusid37089800900
dc.contributor.authorAktaş A.
dc.contributor.authorGüner A.
dc.contributor.authorGüneş O.
dc.contributor.authorKaragül S.
dc.contributor.authorKaraköse O.
dc.contributor.authorMangan Çolak E.
dc.contributor.authorTardu A.
dc.date.accessioned2024-08-04T20:02:18Z
dc.date.available2024-08-04T20:02:18Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThere is limited data on surgical site infection (SSI) in developing countries. The aim of this study was to investigate the incidence and risk factors of SSI following general surgical operations in Türkiye. This multicenter cohort study was conducted at 10 centers. Patients who underwent thyroid/parathyroid, breast, hernia and abdominal surgery between September 2017 and March 2018 were included in the study. Center for Disease Control and Prevention 2016 (CDC-2016) criteria was used for the diagnosis of SSI. Patients were followed for 30 days (90 days for mesh patients). Out of 1871 patients included, SSI occurred in 181 (9.7%) patients. Of these SSI, 101 (55.8%) were superficial, 41 (22.7%) deep, and 39 (21.5%) organ/space SSI. SSI incidence was seen to be high (>15.0%) following some surgeries (40.0% in pancreas, 39.1% in biliary duct, 30.3% in small bowel, 27.9% in colorectal, 27.3% in esophagus, 24.1% in liver, 15.7% in gastric). SSI incidences were generally <5.0% after some surgeries (4.4% in hernia, 4.2% in gallbladder, 3.3% in morbid obesity, 1.4% in breast, 0.8% in thyroid/parathyroid, and zero in spleen and surrenal). In univariate analysis, age ?60 years, female sex, preoperative weight loss, presence of comorbidities, preoperative albumin <3.5 g/dL and hemoglobin <12 g/dL, wound classification, ASA score, general anesthesia, emergency surgery, open surgery, operation time ?4 hours, intraoperative blood loss ?400 ml, perioperative blood transfusion, drain placement, distant infection and malignant disease were associated with SSI. In multivariate analysis preoperative weight loss, clean-contaminated wound, general anesthesia, emergency surgery, open surgical technique, prolonged operation duration (?4 hours), drain placement, and distant infection were found to be independent variable for SSI risk. In order to reduce the incidence of SSI, patients with a weight loss of 10% or more in six months preoperatively should be identified, and nutritional status of the patients should be corrected preoperatively, laparoscopic technique should be preferred in abdominal surgeries, and drain placement should be avoided, especially in clean-contaminated wounds. © 2024 Ondokuz Mayis Universitesi. All rights reserved.en_US
dc.identifier.doi10.52142/omujecm.41.2.24
dc.identifier.endpage369en_US
dc.identifier.issn1309-4483
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85197572953en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage361en_US
dc.identifier.urihttps://doi.org/10.52142/omujecm.41.2.24
dc.identifier.urihttps://hdl.handle.net/11616/91591
dc.identifier.volume41en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherOndokuz Mayis Universitesien_US
dc.relation.ispartofJournal of Experimental and Clinical Medicine (Turkey)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectappendectomyen_US
dc.subjectcolorectalen_US
dc.subjectgastrectomyen_US
dc.subjecthepatopancreatobiliaryen_US
dc.subjectobesityen_US
dc.subjectwound infectionen_US
dc.titleA detailed analysis of surgical site infections and risk factors: A multicentric cohort study in Türkiyeen_US
dc.typeArticleen_US

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