Storage of Allogeneic Vascular Grafts: Experience From a High-Volume Liver Transplant Institute

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dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridince, volkan/0000-0002-0714-490X
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authoridKoc, Cemalettin/0000-0002-5676-6772
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.authorwosidince, volkan/M-7325-2017
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidKoc, Cemalettin/B-6430-2018
dc.contributor.authorAydin, Cemalettin
dc.contributor.authorInce, Volkan
dc.contributor.authorOtan, Emrah
dc.contributor.authorAkbulut, Sami
dc.contributor.authorKoc, Cemalettin
dc.contributor.authorKayaalp, Cuneyt
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:38:01Z
dc.date.available2024-08-04T20:38:01Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAllogeneic vascular grafts are often required for vascular reconstruction during living donor liver transplantation. Such grafts are obtained prior to use, making storage conditions a critical issue for maintaining the integrity of the tissue to ensure a successful transplantation. This study describes an optimized storage protocol currently in use at a high-volume liver transplant center. Twenty-nine allogeneic vascular graft tissues obtained during cardiovascular surgery or from cadaveric donors were stored respectively in sterile 50 mL of Ringer lactate solution, without any preservation solutions or antimicrobials, at -22 degrees C for a maximum of 3 months. Prior to use in vascular reconstruction, grafts were thawed in 0.9% NaCl solution at 37 degrees C, and 1 x 0.5-cm(2) tissue samples were collected for microbial culturing and viral serology. ABO compatibility was not performed for any patients receiving vascular grafts. During this prospective study, all 29 allogeneic vascular grafts were used for back-table vascular reconstruction in living donor liver transplantation procedures. A total of 16 grafts were from the saphenous vein, 10 were from the iliac vein, and 3 were from the iliac artery. Bacterial growth was not detected in any tissue samples taken from the stored grafts. No vascular graft-related complications occurred during the 5 months of follow-up. The successful vascular reconstructions achieved with all 29 study grafts demonstrate that the simple, inexpensive storage method described herein is feasible and safe. Randomized, controlled studies should be carried out to further optimize and standardize the technique.en_US
dc.identifier.doi10.9738/INTSURG-D-12-00035.1
dc.identifier.endpage174en_US
dc.identifier.issn0020-8868
dc.identifier.issue2en_US
dc.identifier.pmid23701155en_US
dc.identifier.scopus2-s2.0-84892370825en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage170en_US
dc.identifier.urihttps://doi.org/10.9738/INTSURG-D-12-00035.1
dc.identifier.urihttps://hdl.handle.net/11616/96319
dc.identifier.volume98en_US
dc.identifier.wosWOS:000325749700014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInt College Of Surgeonsen_US
dc.relation.ispartofInternational Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLiver transplantationen_US
dc.subjectAllogeneic vascular graftsen_US
dc.subjectHomologous graftsen_US
dc.subjectStorage protocolen_US
dc.titleStorage of Allogeneic Vascular Grafts: Experience From a High-Volume Liver Transplant Instituteen_US
dc.typeArticleen_US

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