Sympathetic skin responses in type-1 diabetic children: Relationship to urodynamic findings

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dc.authoridSARIER, Mehmet/0000-0002-8656-7416
dc.authoridakinci, akin/0000-0001-5472-7756
dc.authoridAslan, Mehmet/0000-0001-5710-6592
dc.authoridozcan, abdulcemal/0000-0002-6759-7556
dc.authorwosidSARIER, Mehmet/B-8589-2018
dc.authorwosidakinci, akin/B-1943-2018
dc.authorwosidAslan, Mehmet/AEL-7823-2022
dc.authorwosidSoylu, Ahmet/P-2015-2019
dc.authorwosidozcan, abdulcemal/B-1348-2008
dc.contributor.authorSoylu, A
dc.contributor.authorAkinci, A
dc.contributor.authorYilmaz, U
dc.contributor.authorSarier, M
dc.contributor.authorAslan, M
dc.contributor.authorOman, C
dc.date.accessioned2024-08-04T20:15:25Z
dc.date.available2024-08-04T20:15:25Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAims: Cystopathy is an important problem in diabetes mellitus (DM) when diabetes is not well-controlled. In most cases of diabetic csytopathy, autonomic involvement is responsible, which develops insidiously over a long time. We investigated the hand and genital sympathetic skin responses (SSRs) and its relation to urodynamic abnormalities in this group of patients. Methods: We performed hand and genital SSRs in 24 children with Type-1 DM,whose hemoglobin A1C values were above normal limits. We also recruited 19 healthy children for SSRs measurements. Cystometry was performed in 24 children with Type-1 DM. Based on cystometry findings, these children were classified into two groups as normal (n:6) and abnormal (n:18). The amplitude and latency of hand and genital SSRs of 24 children with Type-1 DM and 19 healthy children were compared. Results: Hand and genital SSRs were obtained from all of the diabetic and healthy children. The mean genital SSRs amplitude in diabetic children was significantly lower than the controls. There was no difference in the mean values of all investigated parameters between the normal group and controls. When compared to the controls, there was prolonged latency and decreased amplitude of genital SSRs and decreased hand SSRs amplitude in abnormal group. Conclusions: SSR is a non-invasive test for the evaluation of autonomic sympathetic involvement. Our study revealed differences in genital SSR before the manifestations of cystopathy. Children with abnormal urodynamic findings had changes in both hand and genital SSRs. These findings suggest that SSR tests may have a place in the evaluation of diabetic cystopathy in the early asymptomatic period.en_US
dc.identifier.doi10.1002/nau.20210
dc.identifier.endpage248en_US
dc.identifier.issn0733-2467
dc.identifier.issn1520-6777
dc.identifier.issue3en_US
dc.identifier.pmid16496392en_US
dc.identifier.scopus2-s2.0-33646512622en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage243en_US
dc.identifier.urihttps://doi.org/10.1002/nau.20210
dc.identifier.urihttps://hdl.handle.net/11616/94377
dc.identifier.volume25en_US
dc.identifier.wosWOS:000237346700007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofNeurourology and Urodynamicsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdiabetic cystopathyen_US
dc.subjectsympathetic skin responsesen_US
dc.subjecturodynamicen_US
dc.titleSympathetic skin responses in type-1 diabetic children: Relationship to urodynamic findingsen_US
dc.typeArticleen_US

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