Changing pH of Bronchoalveolar Lavage Fluid in Patients Undergoing Extracorporeal Circulation

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dc.authoridAlat, Ilker/0000-0003-1860-7620
dc.authorwosidYagdi, Tahir/B-3226-2018
dc.authorwosidAlat, Ilker/AAQ-6262-2021
dc.contributor.authorAlat, Ilker
dc.contributor.authorBayindir, Ulku
dc.contributor.authorOzkisacik, Erdem
dc.contributor.authorTasbakan, Sezai
dc.contributor.authorSaribulbul, Osman
dc.contributor.authorBuket, Suat
dc.contributor.authorYagdi, Tahir
dc.date.accessioned2024-08-04T20:57:21Z
dc.date.available2024-08-04T20:57:21Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractSince bronchoalveolar lavage (BAL) fluid can give a dynamic impression of what is present or developing in situ on the air exchange surface, we worked with BAL fluid to solve the etiopathogenesis of pulmonary complications due to cardiopulmonary bypass (CPB). Forty BAL fluid samples were obtained in 10 patients, undergoing coronary artery bypass grafting (CABG) surgery. Samples were obtained at the following time periods: 1. preoperatively; 2. at the end of the first hour after anesthetic induction; 3. at the conclusion of 30 min. of crossclamp on CPB; 4. 20 h after CPB. Neither calcium nor potassium ions were detectable in any sample. Mean pH of preoperative bronchoalveolar lavage fluid was 6.361 (SD +/- 3,55.10(-2)) and the other mean pH values were 6.375 (SD +/- 0.44), 6.567 (SD +/- 0.165), 6.470 (SD +/- 9,29.10(-2)), respectively. There was not any significant change between the first two steps (p=0.241). Likewise, the change between the third and fourth samples was not statistically significant (p=0.074). However, the change between the second and third studies was statistically significant (p=0.005). And also, the change between preoperative and final studies was statistically significant (p=0.007). The mean recoveries of lavage fluids was about 64% in the first samplings, 75% in the second, 73.4% in the third, and 56% in the fourth. This study reveals that CPB alters one of the main favorable conditions of ecosystem in bronchoalveolar space, namely the pH. Besides, excessive mucous secretion in an involved lung due to CPB which limits making BAL is the reason for atelectasis. As reported in the previous studies, since bronchoalveolar pH changes affect substances like surfactant, this study will set the baseline for further studies.en_US
dc.identifier.endpage56en_US
dc.identifier.issn1302-7808
dc.identifier.issn1308-5387
dc.identifier.issue1en_US
dc.identifier.startpage51en_US
dc.identifier.urihttps://hdl.handle.net/11616/102561
dc.identifier.volume6en_US
dc.identifier.wosWOS:000421579800009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isotren_US
dc.publisherBilimsel Tip Publishing Houseen_US
dc.relation.ispartofTurkish Thoracic Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectheart surgeryen_US
dc.subjectcardiopulmonary bypassen_US
dc.subjectbronchoalveolar lavageen_US
dc.subjectpHen_US
dc.subjectatelectasisen_US
dc.subjectextracorporeal circulationen_US
dc.titleChanging pH of Bronchoalveolar Lavage Fluid in Patients Undergoing Extracorporeal Circulationen_US
dc.typeArticleen_US

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