Effect of receiver shape and volume on the Alzheimer disease for molecular communication via diffusion

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dc.authoridisik, ibrahim/0000-0003-1355-9420
dc.authoridTağluk, M. Emin/0000-0001-7789-6376
dc.authoridDemirkol, Ilker/0000-0002-8026-5337
dc.authoridYILMAZ, H. Birkan/0000-0002-4773-2028
dc.authorwosidisik, ibrahim/AAG-5915-2019
dc.authorwosidTağluk, M. Emin/ABH-1005-2020
dc.authorwosidDemirkol, Ilker/C-7541-2009
dc.authorwosidYILMAZ, H. Birkan/H-3410-2012
dc.contributor.authorIsik, Ibrahim
dc.contributor.authorYilmaz, H. Birkan
dc.contributor.authorDemirkol, Ilker
dc.contributor.authorTagluk, Mehmet Emin
dc.date.accessioned2024-08-04T20:48:59Z
dc.date.available2024-08-04T20:48:59Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractNano-devices are featured to communicate via molecular interaction, the so-called molecular communication (MC). In MC systems, the information is carried by molecules where the amount of molecules constitutes the level of the signal. In this study, an MC-based system was analysed with different receiver topology and related parameters, such as size, shape, and orientation of receptors on the receiver. Also in the concept of nano-medicine, the effect of amyloid-beta (A(beta)), which is believed as the main cause of Alzheimer disease, on the successful reception ratio of molecules with the proposed receiver models was investigated. It was demonstrated that the cubic receiver model is superior to sphere one in terms of the correct reception ratio of the molecular signal. A cubic model where its edge (not rotated around the centre) is placed across the transmitter demonstrated a better performance in reducing the effect of A(beta) as compared to the sphere model while a cubic model where its corner (rotated around the centre) is placed across the transmitter demonstrated a worse performance than the spherical model. From this expression, it may be concluded that with the adjustment of topological system parameters the probability of successful reception ratio in MC may be possible.en_US
dc.description.sponsorshipInonu University Project of Scientific Research Unit (BAP) [FBA-2018-1013]; Scientific and Technical Research Council of Turkey (TUBITAK) [118C274]; Spanish Government, MINECO [RYC-2013-13029]en_US
dc.description.sponsorshipThe work of I. Isik and M. E. Tagluk was supported by the Inonu University Project of Scientific Research Unit (BAP) under the project number FBA-2018-1013. The authors thank HP Turkey section for providing a powerful computer for computational tasks in this study. The work of H.B. Yilmaz is supported by the Scientific and Technical Research Council of Turkey (TUBITAK) under grant no. 118C274. The work of I. Demirkol was supported by the Spanish Government, MINECO, through project RYC-2013-13029.en_US
dc.identifier.doi10.1049/iet-nbt.2019.0300
dc.identifier.endpage608en_US
dc.identifier.issn1751-8741
dc.identifier.issn1751-875X
dc.identifier.issue7en_US
dc.identifier.pmid33010136en_US
dc.identifier.scopus2-s2.0-85092432807en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage602en_US
dc.identifier.urihttps://doi.org/10.1049/iet-nbt.2019.0300
dc.identifier.urihttps://hdl.handle.net/11616/99581
dc.identifier.volume14en_US
dc.identifier.wosWOS:000577098100009en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInst Engineering Technology-Ieten_US
dc.relation.ispartofIet Nanobiotechnologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectdiseasesen_US
dc.subjectmolecular biophysicsen_US
dc.subjectneurophysiologyen_US
dc.subjectprobabilityen_US
dc.subjectreceiver shapeen_US
dc.subjectAlzheimer diseaseen_US
dc.subjectmolecular communicationen_US
dc.subjectnanodevicesen_US
dc.subjectmolecular interactionen_US
dc.subjectsmart medicineen_US
dc.subjectneuronal communicationen_US
dc.subjectMC systemsen_US
dc.subjecthigh signal levelen_US
dc.subjectlow-signal levelen_US
dc.subjecttopological parametersen_US
dc.subjectMC-based systemen_US
dc.subjectnanomedicineen_US
dc.subjectcubic receiver modelen_US
dc.subjectcorrect reception ratioen_US
dc.subjectmolecular signalen_US
dc.subjectcubic modelen_US
dc.subjectspherical modelen_US
dc.subjecttopological system parametersen_US
dc.titleEffect of receiver shape and volume on the Alzheimer disease for molecular communication via diffusionen_US
dc.typeArticleen_US

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