Adenosine deaminase and xanthine oxidase activities in bladder washing fluid from patients with bladder cancer

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dc.authoridYALCIN, OMER TARIK/0000-0001-5626-1881
dc.authorwosidYALCIN, OMER TARIK/B-4744-2018
dc.contributor.authorGüleç, M
dc.contributor.authorAkin, H
dc.contributor.authorYüce, H
dc.contributor.authorErgin, E
dc.contributor.authorElyas, H
dc.contributor.authorYalçin, O
dc.contributor.authorAkyol, Ö
dc.date.accessioned2024-08-04T20:13:29Z
dc.date.available2024-08-04T20:13:29Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractActivities of adenosine deaminase (AD), and xanthine oxidase (XO) enzymes were measured in bladder washing fluid (BWF) from 37 patients with bladder cancer. The patients were divided into several groups according to their sex; pattern, number, and depth of the tumors; and tumor grade. There was a statistically significant difference in XO activities between the patients having no tumor and papillary tumor (p < 0.002). The differences in XO values between the patients having no tumor and single tumor; and with no tumor and multiple tumors were statistically significant (p < 0.012, p < 0.016 respectively). XO activities were increased in patients with both papillary and multiple tumors compared to tumor-free group. Regarding to the depth of tumors, only the differences in XO values between the patients having no tumor and superficial tumor was statistically significant (p < 0.037). XO values of patients in grade 1 were higher than the patients having no tumor (p < 0.010). AD activities in patients with multiple and invasive tumor were increased compared to patients with single and superficial tumor. AD values in grade 3 were lower than grade 2. However, we did not find any statistically significant differences in AD activities in all groups. As a conclusion, increased XO activity in BWF might be a potentially important finding as an additional diagnostic biochemical tool for bladder cancer. But we could not say this for AD activity. Further investigations in a larger cohort of patients with bladder cancer are needed to enlighten the possible diagnostic role of XO and AD in BWF. (C) 2003 The Canadian Society of Clinical Chemists. All rights reserved.en_US
dc.identifier.doi10.1016/s0009-9120(02)00452-6
dc.identifier.endpage196en_US
dc.identifier.issn0009-9120
dc.identifier.issue3en_US
dc.identifier.pmid12726927en_US
dc.identifier.scopus2-s2.0-0242585009en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage193en_US
dc.identifier.urihttps://doi.org/10.1016/s0009-9120(02)00452-6
dc.identifier.urihttps://hdl.handle.net/11616/93656
dc.identifier.volume36en_US
dc.identifier.wosWOS:000182739400005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofClinical Biochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSuperoxide-Dismutaseen_US
dc.subjectCatalase Activitiesen_US
dc.subjectHuman Tissuesen_US
dc.subjectLung-Canceren_US
dc.subjectEnzymesen_US
dc.subjectCarcinomaen_US
dc.subjectIsozymesen_US
dc.titleAdenosine deaminase and xanthine oxidase activities in bladder washing fluid from patients with bladder canceren_US
dc.typeArticleen_US

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