Effect of Pre-Transplant Covid-19 Exposure on Post-Liver Transplant Clinical Outcomes

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dc.authoridBASKIRAN, ADIL/0000-0002-7536-1631
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authoridGARZALI, IBRAHIM UMAR/0000-0002-9797-851X
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridBarut, Bora/0000-0001-9489-5973
dc.authoridBAYINDIR, Yasar/0000-0003-3930-774X
dc.authoridTamer, Murat/0000-0001-9142-1844
dc.authorwosidBASKIRAN, ADIL/ABI-2356-2020
dc.authorwosidSARICI, KEMAL BARIŞ/ABI-4356-2020
dc.authorwosidGARZALI, IBRAHIM UMAR/ITU-1475-2023
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorAkbulut, Sami
dc.contributor.authorBarut, Bora
dc.contributor.authorGarzali, Ibrahim Umar
dc.contributor.authorSarici, Kemal Baris
dc.contributor.authorTamer, Murat
dc.contributor.authorUnsal, Selver
dc.contributor.authorKarabulut, Ertugrul
dc.date.accessioned2024-08-04T20:53:34Z
dc.date.available2024-08-04T20:53:34Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. COVID-19 has led to an unprecedented global health crisis. This situation caused an immediate reduction in solid organ transplantation activity. This study aimed to present the follow-up results of patients with chronic liver disease who underwent liver transplantation (LT) after a history of COVID-19 infection. Methods. Sociodemographic characteristics and clinicopathological data of 474 patients who underwent LT at Inonu University Liver Transplant Institute between March 11, 2020 and March 17, 2022 were prospectively recorded and analyzed retrospectively. Among these, the data of 35 patients with chronic liver disease who were found to be exposed to COVID-19 infection in the pre-LT period were analyzed for this study. Results. The median body mass index, Child score, and Model for end-stage liver disease/ Pediatric end-stage liver disease scores of the 35 patients were calculated as 25.1 kg/m2 (IQR: 7.4), 9 points (IQR: 4), and 16 points (IQR: 10), respectively. Graft rejection occurred in 4 patients at a median of 25 days post-transplant. Five patients underwent retransplantation at a median of 25 days post-transplant. The most common cause of retransplantation is early hepatic artery thrombosis. There were 5 deaths during postoperative follow-up. Mortality developed in 5 (14.3%) patients exposed to COVID-19 infection in the pretransplant period, whereas mortality occurred in 56 (12.8%) patients not exposed to COVID-19 infection. There was no statistically significant difference in mortality between the groups (P = .79). Conclusions. The results of this study showed that exposure to COVID-19 before LT does not affect post-transplant patients and graft survival.en_US
dc.identifier.doi10.1016/j.transproceed.2023.01.024
dc.identifier.endpage1181en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid36973149en_US
dc.identifier.scopus2-s2.0-85151462671en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1176en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2023.01.024
dc.identifier.urihttps://hdl.handle.net/11616/101269
dc.identifier.volume55en_US
dc.identifier.wosWOS:001035779900001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keywords]en_US
dc.titleEffect of Pre-Transplant Covid-19 Exposure on Post-Liver Transplant Clinical Outcomesen_US
dc.typeArticleen_US

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