The impact of splenectomy on human lipid metabolism
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Upsala Med Soc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Splenectomy impacts hematological, immunological, and metabolic functions of the patient. Since our understanding of its metabolic effects, in particular effects on lipid metabolism, is limited, this study aims to investigate the effects of splenectomy on lipid metabolism. Methods: The data from 316 patients undergoing splenectomy between 2009 and 2019 were retrospectively analyzed. Thirty- eight patients whose serum lipid values were measured both preoperatively and 1 year after surgery were included in this study. Results: Significantly higher levels of total cholesterol, low-density lipoprotein (LDL), and non-high-density lipoprotein (HDL) lipid profile were found in the postsplenectomy measurements. However, no significant differences were recorded in levels of triglyceride, HDL, or very-LDL. Conclusion: We determined that splenectomy does impact lipid metabolism, and that the metabolic effects of splenectomy should further be investigated.
Açıklama
Anahtar Kelimeler
atherosclerosis, hyperlipidemia, autotransplantation, homeostasis, coronary, lipoprotein
Kaynak
Upsala Journal of Medical Sciences
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
127
Sayı
1
