Pancreatic involvement in cystic fibrosis
| dc.authorscopusid | 35562819000 | |
| dc.contributor.author | Selimo?lu M.A. | |
| dc.date.accessioned | 2024-08-04T20:02:35Z | |
| dc.date.available | 2024-08-04T20:02:35Z | |
| dc.date.issued | 2011 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Cystic fibrosis (CF) is an autosomal genetic disease causing an accumulation of mucus in many exocrine organs. It is the most frequent cause of exocrine pancreatic insufficiency in childhood. Approximately 85 to 90% of CF patients are pancreatic insufficient (PI), however, there is an increase in the number of CF patients who are pancreatic sufficient (PS). Other than PS and PI groups, an additional third group including PS patients with late conversion from PS to PI has been described. Although there are several ways to determine that conversion, faecal elastase-1 is the ideal marker of endogenous pancreatic secretion. Recurrent acute and chronic pancreatitis is not rare in PS individuals; pancreatitis may be the presenting symptom. In cases with PI, there is a minimal risk of inflammatory or neoplastic changes, whereas a functioning pancreas is at risk of developing pancreatitis. Few cases of pancreatic cancer are reported in CF patients, but overall risk is unknown. Patients with malabsorption should receive pancreatic enzyme replacement, however, if gastrointestinal symptoms and signs are absent or minimal, definitive evidence of malabsorption should first be identified. © Touch Briefings 2011. | en_US |
| dc.identifier.endpage | 53 | en_US |
| dc.identifier.issn | 1758-3799 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopus | 2-s2.0-79954617300 | en_US |
| dc.identifier.scopusquality | N/A | en_US |
| dc.identifier.startpage | 51 | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/91804 | |
| dc.identifier.volume | 7 | en_US |
| dc.indekslendigikaynak | Scopus | en_US |
| dc.language.iso | en | en_US |
| dc.publisher | Touch Briefings | en_US |
| dc.relation.ispartof | European Gastroenterology and Hepatology Review | en_US |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/closedAccess | en_US |
| dc.subject | Cystic fibrosis | en_US |
| dc.subject | Pancreas | en_US |
| dc.title | Pancreatic involvement in cystic fibrosis | en_US |
| dc.type | Article | en_US |
