Diffusion-weighted magnetic resonance imaging in differentiation of postobstructive consolidation from central lung carcinoma

dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.contributor.authorBaysal, Tamer
dc.contributor.authorMutlu, Deniz Yakar
dc.contributor.authorYologlu, Saim
dc.date.accessioned2024-08-04T20:32:12Z
dc.date.available2024-08-04T20:32:12Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose: To prospectively evaluate diffusion-weighted (DW) magnetic resonance (MR) imaging for differentiation of postobstructive consolidation from centrally located lung carcinomas by using apparent diffusion coefficients (ADCs). Materials and Methods: An institutional review board approved this study; informed consent was obtained from patients. Forty-nine consecutive patients (3 women, 46 men; mean age, 63.6 years; age range, 42-85 years) with lung carcinoma underwent DW MR imaging. Forty patients had central and nine patients had peripheral lung carcinomas. ADC of each lung carcinoma was calculated from DW MR images obtained with two different h Values (0, 1000 s/mm(2)). In the final Study group including 27 patients with central lung carcinoma accompanying distal lung consolidation (mean age, 67.2 years, 3 women, 24 men), ADCs Of lung carcinomas were statistically compared among cytologic/histologic types and accompanying postobstructive consolidations. Unpaired t test was used for measurable variables with normal distribution, and Kruskal-Wallis variance analysis and Mann-Whitney U tests were used for the Measurable variables without normal distribution. Results: There was no significant difference between mean ADC values of all types of carcinomas (P=.302) and also between mean ADC values of central (1.91 +/- 0.7 x 10(-3) mm(2)/s) and peripheral carcinomas (1.58 +/- 0.6 x 10(-3) mm(2)/s) (P=.224). The mean ADC value for the masses Of Central lung carcinoma with postobstructive consolidations was 1.83 +/- 0.75 x 10(-3) mm(2)/s, and for consolidation was 2.50 +/- 0.76 x 10(-3) mm(2)/s. ADC of central carcinoma masses was significantly lower than that of postobstructive consolidations (P=.003). Conclusions: A DC values of central lung I I Ling carcinoma masses appear to be lower than accompanying postobstructive consolidations. A DC values Could be considered useful as a differentiating parameter among central lung carcinomas and accompanying postobstructive consolidations. (C) 2009 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.mri.2009.05.024
dc.identifier.endpage1454en_US
dc.identifier.issn0730-725X
dc.identifier.issn1873-5894
dc.identifier.issue10en_US
dc.identifier.pmid19553048en_US
dc.identifier.scopus2-s2.0-70449526535en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1447en_US
dc.identifier.urihttps://doi.org/10.1016/j.mri.2009.05.024
dc.identifier.urihttps://hdl.handle.net/11616/94910
dc.identifier.volume27en_US
dc.identifier.wosWOS:000272119400014en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofMagnetic Resonance Imagingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDW-MRIen_US
dc.subjectPostobstructive consolidationen_US
dc.subjectCentral lung carcinomaen_US
dc.titleDiffusion-weighted magnetic resonance imaging in differentiation of postobstructive consolidation from central lung carcinomaen_US
dc.typeArticleen_US

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