Dendritic cells

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dc.authorscopusid6701663430
dc.authorscopusid7801545386
dc.contributor.authorEşrefo?lu M.
dc.contributor.authorKuruş M.
dc.date.accessioned2024-08-04T19:59:41Z
dc.date.available2024-08-04T19:59:41Z
dc.date.issued2002
dc.departmentİnönü Üniversitesien_US
dc.description.abstractDendritic cells are highly efficient antigen-presenting cells and thus play a crucial role in the immune system. They originate from bone marrow and are found as a trace population in nonlymphoid tissue (Langerghans cells, dermal dendrocytes), in the circulation (blood, afferent lymph) and in lymphoid organs (follicular dendritic cells, interdigitating dendritic cells). Dendritic cells demonstrate a typical dendritic morphology and show an outstanding capacity to initiate primary immune responses. As a consequence of different but not yet fully eluciated stimuli, dendritic cells migrate from the nonlymphoid tissues, where they reside in the immature state, via the afferent lymphatics or the blood to the lymphoid organs. They appear as mature dendritic cells. According to their specific location and their state of maturation, dendritic cells have distinct morphological, phenotypic and functional properties. Pathogens, cytokines, chemokines and lipopolysaccharide can induce the differentiation of immature dendritic cells into mature dendritic cells, which have decreased capacity for antigen processing but increased capacity for antigen presentation. We tried to review the subpopulations, morphological, physiological and functional features and localizations of the dendritic cells.en_US
dc.identifier.endpage135en_US
dc.identifier.issn1016-5134
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-0036309577en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage129en_US
dc.identifier.urihttps://hdl.handle.net/11616/90821
dc.identifier.volume14en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofSENDROMen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantigen presentationen_US
dc.subjectantigen presenting cellen_US
dc.subjectbone marrowen_US
dc.subjectcell differentiationen_US
dc.subjectcell migrationen_US
dc.subjectcell structureen_US
dc.subjectcell subpopulationen_US
dc.subjectdendritic cellen_US
dc.subjectimmune responseen_US
dc.subjectimmune systemen_US
dc.subjectLangerhans cellen_US
dc.subjectlymphoid organen_US
dc.subjectphenotypeen_US
dc.subjectshort surveyen_US
dc.titleDendritic cellsen_US
dc.title.alternativeDendritik hücrelerin morfolojik ve fonksiyonel özelliklerien_US
dc.typeShort Surveyen_US

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