Does the intraoperative parathormone monitoring really affect surgical success in primary hyperparathyroidism?

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dc.authoridOZDEMIR, EGEMEN/0000-0002-8022-8245
dc.authoridTutuncu, Tanju/0000-0001-9058-465X
dc.authorwosidOZDEMIR, EGEMEN/GVT-6777-2022
dc.authorwosidTutuncu, Tanju/CAF-0280-2022
dc.contributor.authorOzdemir, Egemen
dc.contributor.authorOzden, Sabri
dc.contributor.authorTutuncu, Tanju
dc.contributor.authorDaglar, Gul
dc.contributor.authorYuksek, Yunus Nadi
dc.date.accessioned2024-08-04T20:50:25Z
dc.date.available2024-08-04T20:50:25Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Surgery is the only curative treatment option for primary hyperparathyroidism (PHPT). The intraoperative parathormone (IOPTH) monitoring is recommended to confirm that all pathological glands have been removed. This study aimed to evaluate the effect of IOPTH monitoring on the surgical success of parathyroidectomy performed for PHPT. Methods The demographic, biochemical, operative and pathological data of patients who underwent parathyroidectomy for PHPT in a single institute over a three-year period were retrospectively analyzed. Results The total number of patients included in the study was 182. The IOPTH monitoring had been performed in 92 patients (50.5%). The IOPTH monitoring had a clinical accuracy of 89.2%, sensitivity of 89.8%, and specificity of 75%. The rate of surgical success was 95.7% in the group with IOPTH monitoring and 91.1% in the group without this monitoring (p = .21). Of the 40 patients who underwent minimally invasive parathyroidectomy (MIP), 25 patients had IOPTH monitoring, and the surgery was successful for all these patients (100%). Surgical success was achieved in 14 (93.3%) patients who underwent MIP without IOPTH monitoring (p = .37). Conclusion The IOPTH monitoring is a reliable test with high accuracy. The lack of IOPTH monitoring may result in lower than acceptable surgical success rates. Even though preoperative localization studies are compatible with surgical findings, the IOPTH monitoring should also be undertaken, especially in patients scheduled for MIP for PHPT.en_US
dc.identifier.doi10.1080/00015458.2021.1955185
dc.identifier.endpage123en_US
dc.identifier.issn0001-5458
dc.identifier.issue2en_US
dc.identifier.pmid34253156en_US
dc.identifier.scopus2-s2.0-85110831539en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage118en_US
dc.identifier.urihttps://doi.org/10.1080/00015458.2021.1955185
dc.identifier.urihttps://hdl.handle.net/11616/100055
dc.identifier.volume123en_US
dc.identifier.wosWOS:000674776100001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Chirurgica Belgicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPrimary hyperparathyroidismen_US
dc.subjectparathyroidectomyen_US
dc.subjectparathormoneen_US
dc.subjectintraoperative monitoringen_US
dc.titleDoes the intraoperative parathormone monitoring really affect surgical success in primary hyperparathyroidism?en_US
dc.typeArticleen_US

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