A long-lasting Sphingomonas paucimobilis outbreak: A potential for pathogens to persist on environmental devices despite disinfection measures

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dc.authoridOTLU, BARIS/0000-0002-6220-0521
dc.authoridTanriverdi, Elif Seren/0000-0002-0449-0356
dc.authoridKırali, Mehmet Kaan/0000-0003-0044-4691
dc.authorwosidOTLU, BARIS/ABI-5532-2020
dc.authorwosidTanriverdi, Elif Seren/ABE-4472-2021
dc.authorwosidKırali, Mehmet Kaan/ABH-2067-2020
dc.contributor.authorMenekse, Sirin
dc.contributor.authorTanriverdi, Elif Seren
dc.contributor.authorAltinay, Ece
dc.contributor.authorOgus, Halide
dc.contributor.authorAydogan, Arzu Atesoglu
dc.contributor.authorSaglam, Duygu
dc.contributor.authorCelik, Ozge
dc.date.accessioned2024-08-04T20:53:13Z
dc.date.available2024-08-04T20:53:13Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Sphingomonas paucimobilis, an aerobic, non-fermentative, Gram-negative opportunistic bacillus, can colonize everywhere in hospital settings where water is used. We reported a hospital S paucimobilis outbreak that persisted for nearly 2 years despite all necessary preventive measures.Methods: Over a period from February 13, 2020 to December 3, 2021, 67 patients were identified to have S paucimobilis as documented by positive cultures from clinical samples, along with 19 positive environmental samples.Results: Bacterial regrowth for molecular analysis could be obtained in 49 isolates (39 clinical, 4 extracorporeal membrane oxygenation (ECMO) water heater devices, 1 unused mouthwash solution, 5 water samples from thoracic drainage aspirators). Two distinct clonally indistinguishable genotypes were detected in APPCR and PFGE analyses, with 100% consistency. The main cluster was obtained consistently throughout the outbreak from 30 samples (61.2%: 24 clinical, 4 ECMO, 1 unused mouthwash solution, 1 water sample from the thoracic drainage aspirator). The other cluster involved 15 clinical samples and 4 water samples from the thoracic drainage aspirators.Conclusions: Given that waterborne pathogens can spread to a wide range of equipment used in healthcare environments, the pathogens can persist on the surfaces of environmental devices even after recommended disinfection measures have been applied. Therefore, individual tracking of all devices used in critical care settings, such as thoracic drainage aspirators and ECMO water heater devices, with records of pre- and post-disinfection procedures is of paramount importance for complete elimination of the source of infection. & COPY; 2022 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajic.2022.10.012
dc.identifier.endpage771en_US
dc.identifier.issn0196-6553
dc.identifier.issn1527-3296
dc.identifier.issue7en_US
dc.identifier.pmid36370866en_US
dc.identifier.scopus2-s2.0-85143271111en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage765en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajic.2022.10.012
dc.identifier.urihttps://hdl.handle.net/11616/101033
dc.identifier.volume51en_US
dc.identifier.wosWOS:001053442900001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMosby-Elsevieren_US
dc.relation.ispartofAmerican Journal of Infection Controlen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHospital outbreaken_US
dc.subjectSphingomonas paucimobilisen_US
dc.subjectECMO water heateren_US
dc.subjectThoracic drainage aspiratoren_US
dc.subjectMouthwash solutionen_US
dc.titleA long-lasting Sphingomonas paucimobilis outbreak: A potential for pathogens to persist on environmental devices despite disinfection measuresen_US
dc.typeArticleen_US

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