Comparison of the effects of injectable platelet-rich fibrin and autologous fibrin glue applications on palatal wound healing: a randomized controlled clinical trial

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dc.authoriduslu, mustafa özay/0000-0002-9707-1379
dc.authoridkiziltoprak, mehmet/0000-0001-5829-4812
dc.authorwosiduslu, mustafa özay/S-7657-2019
dc.authorwosidkiziltoprak, mehmet/JOZ-3918-2023
dc.contributor.authorKiziltoprak, Mehmet
dc.contributor.authorUslu, Mustafa Ozay
dc.date.accessioned2024-08-04T20:47:18Z
dc.date.available2024-08-04T20:47:18Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective The aim of this study was to compare the effects of AFG and i-PRF on palatal wound healing and postoperative discomfort. Materials and methods Thirty-six patients in need of FGG were divided into three groups. AFG (n = 12) or i-PRF (n = 12) was applied and compared with control group (n = 12). Wound healing with H2O2 test, VAS, MSS, and LTH index were evaluated on the 3rd,7th, and 14th days and 1st month. The bleeding status was evaluated on the 3rd and 7th days. Palatal tissue thickness was measured at baseline, 1st month, and 3rd month. Results Epithelialization was higher in the test groups on the 14th day than the control group (p < 0.05). MSS scores at the 14th day and 1st month were lower in the AFG group than the control and the i-PRF group (p < 0.05). In the AFG group, LTH levels at the 3rd,7th, and 14th days and 1 month were higher than control and i-PRF groups (p < 0.05). VAS scores of the AFG group were lower than the control and i-PRF groups at the 7th day (p < 0.05). Bleeding was lower in the test groups than in the control group (p < 0.05). There was no difference between the groups in terms of tissue thickness (p > 0.05). Conclusion AFG and i-PRF have positive effects on the healing process by accelerating wound healing and reducing postoperative morbidity. Therewithal, AFG has superior properties in wound healing compared with i-PRF.en_US
dc.identifier.doi10.1007/s00784-020-03320-6
dc.identifier.endpage4561en_US
dc.identifier.issn1432-6981
dc.identifier.issn1436-3771
dc.identifier.issue12en_US
dc.identifier.pmid32424462en_US
dc.identifier.scopus2-s2.0-85084828967en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage4549en_US
dc.identifier.urihttps://doi.org/10.1007/s00784-020-03320-6
dc.identifier.urihttps://hdl.handle.net/11616/99285
dc.identifier.volume24en_US
dc.identifier.wosWOS:000533821900003en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofClinical Oral Investigationsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFree gingival graften_US
dc.subjectInjectable platelet-rich fibrinen_US
dc.subjectPainen_US
dc.subjectPlatelet concentratesen_US
dc.subjectWound epithelizationen_US
dc.titleComparison of the effects of injectable platelet-rich fibrin and autologous fibrin glue applications on palatal wound healing: a randomized controlled clinical trialen_US
dc.typeArticleen_US

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